ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Pyridine derivatives 2-Fluoronicotinic acid

2-Fluoronicotinic acid

2-Fluoronicotinic acid Basic information
Product Name:2-Fluoronicotinic acid
Synonyms:TIMTEC-BB SBB004159;RARECHEM AL BO 2399;2-Fluoronicotinicacid,98+%;2-FLUORO-3-PYRIDINECARBOXYLIC ACID;2-Fluoro-3-pyridinecarboxylic acid(2-Fluoronicotinic acid);2-FLUOROPYRIDINE-3-CARBOXYLIC ACID;2-FLUORONICOTINIC ACID;2-Fluoro-3-NicotinicAcid
CAS:393-55-5
MF:C6H4FNO2
MW:141.1
EINECS:206-888-8
Product Categories:C6;Chemical Synthesis;Picolinic acid series;Fluorinated Building Blocks;Heterocyclic Building Blocks;Morpholines/Thiomorpholines;Pyridines;Building Blocks;Carboxy;Fluoropyridines;Halopyridines;Carboxylic Acids;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles;Pyridine;Boronic Acid
Mol File:393-55-5.mol
2-Fluoronicotinic acid Structure
2-Fluoronicotinic acid Chemical Properties
Melting point 161-165 °C(lit.)
Boiling point 298.7±20.0 °C(Predicted)
density 1.419±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka2.54±0.10(Predicted)
form Powder or Crystalline Powder
color White to yellow
BRN 3612
InChIKeyLLLVHTWJGWNRBD-UHFFFAOYSA-N
CAS DataBase Reference393-55-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,F
Risk Statements 36/37/38-10
Safety Statements 26-36-16
WGK Germany 3
HazardClass IRRITANT
HS Code 29333990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
2-Fluoronicotinic acid Usage And Synthesis
Chemical PropertiesLight yellow Cryst
Uses2-Fluoronicotinic Acid is an intermediate used to prepare oxadiazole derivatives to inhibit tubulin polymerization and to cause mitotic arrest in tumor cells. It is also used to synthesize potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.
2-Fluoronicotinic acid Preparation Products And Raw materials
Preparation Products2-Hydroxynicotinic acid-->2-fluoro-N-methoxy-N-methylnicotinamide
2-Fluoro-6-phenylpyridine-3-carboxylic acid 5-CHLORO-2-FLUORONICOTINIC ACID METHYL 2-FLUOROPYRIDINE-4-BORONIC ACID PINACOL ESTER-3-CARBOXYLATE 2-FLUORO-4-HYDROXYNICOTINIC ACID 2-FLUORONICOTINIC ACID METHYL ESTER 5-BROMO-2-FLUORONICOTINIC ACID 6-FLUORONICOTINIC ACID METHYL ESTER 2-FLUORO-4-IODONICOTINIC ACID METHYL 2,6-DIFLUORONICOTINATE 2,4-DIFLUORO-NICOTINIC ACID 2,5-Difluoropyridine-3-carboxylic acid 2,5,6-Trifluoro-nicotinic acid 2-Fluoro-4-(trifluoromethyl)pyridine-3-carboxylicacid 2-Fluoronicotinic acid 2,6-Difluoropyridine-3-carboxylic acid 2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER 5,6-difluoronicotinic acid 2,5-DIFLUORO-4-CHLORO NICOTINIC ACID
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