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| | 7-Ethylcamptothecin Basic information |
| Product Name: | 7-Ethylcamptothecin | | Synonyms: | IRINOTECAN EP IMPURITY F (7-ETHYL CAMPTOTHECIN);(S)-4,11-diethyl-4-hydroxy-1H;7-Ethylcamptothecin 78287-27-1;Irinotecan EP Impurity F;(S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione;(4S)-4,11-Diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;SN 22;7-Ethylcamptotrecin | | CAS: | 78287-27-1 | | MF: | C22H20N2O4 | | MW: | 376.41 | | EINECS: | | | Product Categories: | Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 78287-27-1.mol |  |
| | 7-Ethylcamptothecin Chemical Properties |
| Melting point | 236-241°C | | Boiling point | 752.9±60.0 °C(Predicted) | | density | 1.43 | | storage temp. | Sealed in dry,2-8°C | | solubility | Chloroform and Methanol Mixture (Slightly, Heated, Sonicated), DMSO (Slightly, Heated) | | pka | 11.24±0.20(Predicted) | | form | Solid | | color | Pale Yellow to Light Orange | | InChIKey | MYQKIWCVEPUPIL-JOCHJYFZSA-N | | CAS DataBase Reference | 78287-27-1(CAS DataBase Reference) |
| Risk Statements | 23/34/35 | | Safety Statements | 3/14-6-36/37/39 | | RIDADR | 1544 | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29349990 |
| | 7-Ethylcamptothecin Usage And Synthesis |
| Chemical Properties | Light Pink Solid | | Uses | An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. Irinotecan USP Related Compound E. | | Definition | ChEBI: 7-ethylcamptothecin is a pyranoindolizinoquinoline. | | Biological Activity | 7-Ethylcamptothecin is one of the camptothecin analogs. Camptothecin (CPT), a cytotoxic alkaloid isolated from camptothecin analogues, has strong antitumor activity against L1210 leukemia and Walker 256 carcinosarcoma models. |
| | 7-Ethylcamptothecin Preparation Products And Raw materials |
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