Dipivefrin hydrochloride

Dipivefrin hydrochloride Basic information
Product Name:Dipivefrin hydrochloride
Synonyms:dipivalylepinephrinehydrochloride;dipivefrinehydrochloride;dipivefrinhydrochloride;hydrochloride,(+-)-este;propanoicacid,2,2-dimethyl-,4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene;Progate;Propanoic acid,2,2-diMethyl-, 1,1'-[4-[1-hydroxy-2-(MethylaMino)ethyl]-1,2-phenylene] ester,hydrochloride (1:1);DIPIVEFRIN HYDROCHLORIDE (200 MG)
CAS:64019-93-8
MF:C19H30ClNO5
MW:387.8982
EINECS:264-609-5
Product Categories:API
Mol File:64019-93-8.mol
Dipivefrin hydrochloride Structure
Dipivefrin hydrochloride Chemical Properties
Melting point 158-159°
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Freely soluble in water, very soluble in methanol, freely soluble in ethanol (96 per cent) and in methylene chloride.
pka8.40(at 25℃)
form neat
color White to Off-White
InChIInChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H
InChIKeyVKFAUCPBMAGVRG-UHFFFAOYSA-N
SMILESC1(OC(=O)C(C)(C)C)=CC(=CC=C1OC(=O)C(C)(C)C)C(O)CNC.Cl
Safety Information
RIDADR UN 2811 6.1 / PGIII
HS Code 2922504500
MSDS Information
Dipivefrin hydrochloride Usage And Synthesis
DescriptionDipivefrin hydrochloride is an antiglaucoma prothrombotic drug that is hydrolyzed to its active compound epinephrine by esterases in the cornea.
Chemical PropertiesWhite or almost white, crystalline powder.
UsesDipivefrine Hydrochloride acts as an anti-glaucoma agent.
UsesAdrenergic (ophthalmic)
DefinitionChEBI: The hydrochloride salt of dipivefrin. It is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.
Brand nameAkpro (Akorn); Propine (Allergan).
in vivoDipivefrin hydrochloride (0.3-10 μg/kg; i.p.;) induces enhancement of memory involves central beta- but not alpha-adrenergic mechanisms.
Dipivefrin hydrochloride Preparation Products And Raw materials
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