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| | Elemicin Basic information |
| Product Name: | Elemicin | | Synonyms: | 5-ALLYL-1,2,3-TRIMETHOXYBENZENE;ELIMICIN;ELEMICIN;1,2,3-trimethoxy-5-(2-propenyl)-benzen;1,2,3-trimethoxy-5-allylbenzene (elemicin);3,4,5-Trimethoxyallylbenzene;4-allyl-1,2,6-trimethoxybenzene;5-allyl-1,2,3-trimethoxy-benzen | | CAS: | 487-11-6 | | MF: | C12H16O3 | | MW: | 208.25 | | EINECS: | 207-649-0 | | Product Categories: | Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 487-11-6.mol |  |
| | Elemicin Chemical Properties |
| Boiling point | 152-156 °C | | density | 1.0630 g/cm3 | | storage temp. | Amber Vial, -20°C Freezer | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Oil | | color | Colourless | | Odor | at 100.00 %. spice flower | | Odor Type | spicy | | Stability: | Light Sensitive | | LogP | 2.298 (est) | | NIST Chemistry Reference | Benzene, 1,2,3-trimethoxy-5-(2-propenyl)-(487-11-6) |
| | Elemicin Usage And Synthesis |
| Description | Elemicin is a trioxygenated phenylpropane that has been found in A. dracunculus. It is active against S. aureus, B. subtilis, and C. albicans (MICs = 600, 2,500, and 1,000 mg/L, respectively) but not E. coli, K. pneumoniae, P. aeruginosa (MICs = >8,000 mg/L for all), or L. monocytogenes (MIC = >3,000 mg/L). Elemicin is toxic to mice following metabolic activation to 1’-hydroxyelemicin by the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. It increases plasma and hepatic triglyceride levels, decreases stearoyl-CoA desaturase 1 (Scd1) expression, and induces hepatomegaly in mice when administered at a dose of 500 mg/kg per day for three weeks. | | Chemical Properties | Clear Colorless Oil | | Uses | A constituent of the essential oil of nutmeg and is responsible for the psychoactive effects of nutmeg. Also a minor constituent of the oleoresin and essential oil of Manila elemi (Canarium luzonicum). Exhibits anticholinergic-like effects in humans. | | Definition | ChEBI: Elemicin is an olefinic compound. | | target | Antifection |
| | Elemicin Preparation Products And Raw materials |
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