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Pamoic acid

Pamoic acid Basic information
Product Name:Pamoic acid
Synonyms:PAMOIC ACID;EMBIONIC ACID;2-Naphthalenecarboxylic acid, 4,4-methylenebis3-hydroxy-;1,1'-methylene-bis(2-hydroxy-3-naphthoic acid);PAMOIC ACID pure;1,1μ-Methylene-bis(2-hydroxy-3-naphthoic acid), 4,4μ-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid;Bis(2-hydroxy-3-carboxy-1-naphthyl)methane;Pamoic Acid (250 mg)
CAS:130-85-8
MF:C23H16O6
MW:388.37
EINECS:204-998-0
Product Categories:Antiparasitic Agents;Bioactive Small Molecules;Biochemicals and Reagents;Building Blocks;C13 to C42+;Carbonyl Compounds;Carboxylic Acids;Cell Biology;Chemical Synthesis;Fatty Acids and conjugates;Fatty Acyls;Lipids;Organic Building Blocks;P;Straight Chain Fatty Acids;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:130-85-8.mol
Pamoic acid Structure
Pamoic acid Chemical Properties
Melting point ≥300 °C (dec.)
Boiling point 434.1°C (rough estimate)
density 1.2472 (rough estimate)
refractive index 1.4593 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in nitrobenzene, pyridine
form Crystalline Powder
pka2.67±0.30(Predicted)
color Yellow to yellow-green
Water Solubility PRACTICALLY INSOLUBLE
Merck 14,7005
BRN 901319
InChIKeyWLJNZVDCPSBLRP-UHFFFAOYSA-N
CAS DataBase Reference130-85-8(CAS DataBase Reference)
EPA Substance Registry System2-Naphthalenecarboxylic acid, 4,4'-methylenebis[3-hydroxy- (130-85-8)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-48-41-37/38-20/21/22
Safety Statements 26-36-45-36/37/39-22
WGK Germany 3
RTECS QL2180000
TSCA Yes
HS Code 29182990
Toxicityeye-rbt 100 mg MOD FCTOD7 20,573,82
MSDS Information
ProviderLanguage
Embonic acid English
SigmaAldrich English
ACROS English
ALFA English
Pamoic acid Usage And Synthesis
Chemical PropertiesPamoic acid is yellow to yellow-green crystalline powder
UsesPamoic acid is used in preparation of repository derivatives of medicinal agents, used in pharmacology to increase the solubility of a drug in water.
UsesAgonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases.
DefinitionChEBI: Pamoic acid is a dicarboxylic acid. It is functionally related to a 2-naphthoic acid. It is a conjugate acid of a pamoate(2-).
General DescriptionPharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Safety ProfilePoison by intraperitoneal route. An eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Pamoic acid Preparation Products And Raw materials
Preparation ProductsCiprofloxacin hydrochloride
EMBONIC ACID(RG) Pamoic Acid Disodium Salt (Embonic Acid, disodium salt monohydrte),Pamoic Acid Disodium Salt (Embonic Acid, disodium salt monohydrte) Pamoic acid disodium salt Ethyl 2-(Chlorosulfonyl)acetate PAMOIC ACID, DISODIUM SALT MONOHYDRATE, 98 2'-Hydroxy-3-phenylpropiophenone Ascoric Acid PAMOIC ACID, K 3-Hydroxybenzoic acid PAMOIC ACID DISODIUM SALT HYDRAT Pamoic Acid (Embonic Acid),Pamoic Acid (Embonic Acid) Bufexamac PAMOIC ACID USP(CRM STANDARD) PAMOIC ACID, DISODIUM SALT MONOHYDRATE,EMBONIC ACID, DISODIUM SALT MONOHYDRATE PAMOIC ACID AND SALTS EMBONIC ACID(REAGENT / STANDARD GRADE) CHLOROPHOSPHONAZO III Pyrantel pamoate
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