2-CHLORO-1,1,1-TRIFLUOROETHANE

2-CHLORO-1,1,1-TRIFLUOROETHANE Basic information
Product Name:2-CHLORO-1,1,1-TRIFLUOROETHANE
Synonyms:Chlorotrifluoro ethane;HCFC-133A;FC-133A;2-chloro-1,1,1-trifluoroethane(hcfc-133a);CF3CH2Cl;CFC 133a;cfc133a;chloro-1,1,1-trifluoroethane
CAS:75-88-7
MF:C2H2ClF3
MW:118.49
EINECS:200-912-0
Product Categories:HCFC;refrigerants
Mol File:75-88-7.mol
2-CHLORO-1,1,1-TRIFLUOROETHANE Structure
2-CHLORO-1,1,1-TRIFLUOROETHANE Chemical Properties
Melting point -105°C
Boiling point 7°C
density 1.389
refractive index 1.3090
form A liquid
CAS DataBase Reference75-88-7(CAS DataBase Reference)
IARC3 (Vol. 41, Sup 7, 71) 1999
EPA Substance Registry SystemHCFC-133a (75-88-7)
Safety Information
Hazard Codes Xi
Risk Statements 59
Safety Statements 9-23-59
RIDADR 1983
Hazard Note Irritant
TSCA T
HazardClass 2.2
Hazardous Substances Data75-88-7(Hazardous Substances Data)
ToxicityLCLo inhalation in guinea pig: 33000ppm/5H
MSDS Information
2-CHLORO-1,1,1-TRIFLUOROETHANE Usage And Synthesis
Chemical PropertiesHCFC 133a is odorless with poor warning properties.
UsesHCFC133a is a nonisolated intermediate in the production of halothane.
DefinitionChEBI: 2-Chloro-1,1,1-trifluoroethane is an organofluorine compound.
Synthesis Reference(s)Journal of the American Chemical Society, 70, p. 758, 1948 DOI: 10.1021/ja01182a096
General Description2-CHLORO-1,1,1-TRIFLUOROETHANE is a colorless, odorless gas. 2-CHLORO-1,1,1-TRIFLUOROETHANE is shipped as a liquid under its own vapor pressure. Contact with the liquid may cause frostbite to unprotected skin. 2-CHLORO-1,1,1-TRIFLUOROETHANE can asphyxiate by the displacement of air. Exposure of the container to fire or heat can cause 2-CHLORO-1,1,1-TRIFLUOROETHANE to rupture violently and rocket.
Reactivity Profile2-CHLORO-1,1,1-TRIFLUOROETHANE is chemically inert in many situations, but can react violently with strong reducing agents such as the very active metals and the active metals. Undergoes oxidation with strong oxidizing agents and under extremes of temperature.
Health HazardVapors may cause dizziness or asphyxiation without warning. Vapors from liquefied gas are initially heavier than air and spread along ground. Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite. Fire may produce irritating, corrosive and/or toxic gases.
Fire HazardSome may burn but none ignite readily. Containers may explode when heated. Ruptured cylinders may rocket.
Safety ProfileA poison by inhalation. Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of F-.
CarcinogenicityHCFC 133a was evaluated in a carcinogenesis screening study using Wistar-derived rats. The rats were given daily intubations of 300mg HCFC of body weight in corn oil for 52 weeks and held for a total of 125 weeks. In the males, there was a reduction in body weight gain and testicular size, also there was an increase in Leydig cell tumors and arrest of spermatogenesis. In the females, there was an increased incidence of uterine carcinomas.
1,1,1,3-TETRAFLUORO-2,2,3,3-TETRACHLOROPROPANE 2-Chloro-1,1,1,2-tetrafluoroethane 1,1-Dibromo-1-chloro-2,2,2-trifluoroethane 2,3-DICHLOROHEXAFLUORO-2-BUTENE 2-CHLOROPENTAFLUOROPROPENE HEXAFLUORO-2,2,3,3-TETRACHLOROBUTANE 2-CHLORO-1,1,1-TRIFLUOROETHANE 1,1-DICHLOROTETRAFLUOROETHANE Chloropentafluoroethane 1,1-Dichloro-2,2,2-trifluoroethane 2,3-DICHLOROOCTAFLUOROBUTANE 1,1,2-TRICHLORO-3,3,3-TRIFLUOROPROPENE 1,2-DICHLOROHEXAFLUOROPROPANE Trifluoroacetyl chloride Halothane 2-CHLORO-1,1,1-TRIFLUOROETHANE,1-CHLORO-2,2,2-TRIFLUOROETHANE 2-CHLOROHEPTAFLUOROPROPANE 3-CHLOROHEPTAFLUORO-2-BUTENE

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