ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate

tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate

tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate Basic information
Product Name:tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate
Synonyms:Fluvastatin intermediate F4;Intermediate of Fluvastatin;t-Butyl-(±)-(E)-7-[3`-(4``-fluoro-phenyl)-1`-(1``-methylethyl)indol-2`-yl]-3,5-dihydroxy-6-heptenoate;7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid 1,1-dimethylethyl ester;tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate;FDH: FLUVASTATIN INTERMEDIATE;FLUVASTATIN T-BUTYL ESTER;(3R,5S)-Fluvastatin tert-Butyl Ester
CAS:194934-96-8
MF:C28H34FNO4
MW:467.57
EINECS:
Product Categories:Aromatics;Chiral Reagents;Heterocycles
Mol File:194934-96-8.mol
tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4
tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate Chemical Properties
Melting point 135-138°C
Boiling point 642.3±55.0 °C(Predicted)
density 1.13
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Ethyl Acetate (Slightly),Methanol (Slightly)
pka13.90±0.20(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate Usage And Synthesis
Chemical PropertiesWhite Solid
Uses(3R,5S)-Fluvastatin tert-Butyl Ester (Fluvastatin EP Impurity B) is an intermediate for the preparation of (3R,5S)-Fluvastatin.
tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate Preparation Products And Raw materials
Preparation ProductsSRI 62320
Fluvastatin EP impurity A -G Fluvastatin EP Impurity E rac 5-Keto Fluvastatin Fluvastatin Degradation Product (diastereomeric mixture) Fluvastatin EP Impurity C 3-(4-FLUORO-PHENYL)-1-ISOPROPYL-1H-INDOLE-2-CARBALDEHYDE Fluvastatin 3-Hydroxy-4,6-diene Fluvastatin lactone (racemic mixture) Flurbiprofen Fluvastatin methyl ester Fludarabine (R)-2-Flurbiprofen FLURBIPROFEN AXETIL Fluvastatin Impurity 1 tert-Butyl (E)-3,5-dihydroxy-7-[3'-(4''-fluorophenyl)-1'-methylethyl-indol-2'-yl]-6-heptenoate tert-Butyl (E)-3,5-Dihydroxy-7-[3'-(4"-fluorophenyl)-1'-methylethylindol-2'-yl)hept-6-enoate 3-HEPTENOIC ACID Fluvastatin
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