|  | |  |  | SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Basic information | 
 | Product Name: | SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 |  | Synonyms: | SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9;3,7,12-trihydroxy-, monosodium salt;3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt;Cholalic acid sodium salt;SODIUM CHOLATE HYDRATE, 98 %;SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 96.0% NT DRY MATTER;SODIUM CHOLATE HYDRATE, CELL CULTURE TESTED;SODIUM CHOLATE HYDRATE, PURUM, >= 97.0% NT DRIED MATERIAL |  | CAS: | 206986-87-0 |  | MF: | C24H43NaO6 |  | MW: | 450.59 |  | EINECS: | 206-643-5 |  | Product Categories: |  |  | Mol File: | 206986-87-0.mol |  |  | 
|  |  | SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Chemical Properties | 
 | RTECS | FZ9600000 |  | storage temp. | Store at RT. |  | solubility | H2O: 0.1 M, clear |  | form | Powder |  | color | White |  | optical activity | [α]20/D +36±2°, c = 0.6% in ethanol (dry matter) |  | Water Solubility | Soluble in water. |  | BRN | 3582354 | 
| Safety Statements | 24/25 |  | WGK Germany | 3 |  | F | 3-9 |  | TSCA | Yes |  | HS Code | 29181990 | 
|  |  | SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Usage And Synthesis | 
 | Uses | Biochemical solubilizing agent Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins. It is involved in the study to assess infiltration of pressurized promoter solutions in a mesoporous silica. Further, it serves as a biochemical solubilizing agent. |  | Uses | Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes. |  | Uses | Non-denaturing detergent used for extraction of membrane proteins. |  | General Description | Sodium cholate hydrate is a non-denaturing, anionic detergent. |  | Biochem/physiol Actions | Reduction in 12-α hydroxylase activity leads to low levels of cholic acid in liver disease. | 
|  |  | SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Preparation Products And Raw materials | 
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