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2,4-Dihydroxypyrimidine-5-carboxylic acid

2,4-Dihydroxypyrimidine-5-carboxylic acid Basic information
Product Name:2,4-Dihydroxypyrimidine-5-carboxylic acid
Synonyms:1,2,3,4-TETRAHYDRO-2,4-DIOXO-5-PYRIMIDINECARBOXYLIC ACID;2,4-DIHYDROXYPYRIMIDINE-5-CARBOXYLIC ACID;5-CARBOXY-2,4-DIHYDROXYPYRIMIDINE;5-CARBOXYURACIL extrapure;2,4-Dioxo-11,2,3,4-tetrahydropyrimidine-5-carboxylic acid;2,4-Dioxo-1H-pyrimidine-5-carboxylic acid;5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-;1,2,3,6-Tetrahydro-2,6-dioxo-5-pyrimidinecarboxylic acid
CAS:23945-44-0
MF:C5H4N2O4
MW:156.1
EINECS:245-947-2
Product Categories:Heterocycle-Pyrimidine series;Bases & Related Reagents;Nucleotides;Carboxylic Acids;Pyrazines, Pyrimidines & Pyridazines;Carboxylic Acids;Pyrazines, Pyrimidines & Pyridazines;Pyridine;Nucleotides and Nucleosides
Mol File:23945-44-0.mol
2,4-Dihydroxypyrimidine-5-carboxylic acid Structure
2,4-Dihydroxypyrimidine-5-carboxylic acid Chemical Properties
Melting point 283 °C (dec.)(lit.)
Boiling point 280.29°C (rough estimate)
density 1.6814 (rough estimate)
refractive index 1.4800 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in DMSO
pka5.08±0.20(Predicted)
form Crystalline Powder
color White to slightly yellow
Water Solubility 1.8g/L(20 ºC)
CAS DataBase Reference23945-44-0(CAS DataBase Reference)
EPA Substance Registry System5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo- (23945-44-0)
Safety Information
Risk Statements 36/37/38
Safety Statements 24/25
WGK Germany 3
TSCA Yes
HS Code 29335990
MSDS Information
ProviderLanguage
Uracil-5-carboxylic acid English
SigmaAldrich English
2,4-Dihydroxypyrimidine-5-carboxylic acid Usage And Synthesis
Chemical Propertieswhite to slightly yellow crystalline powder or
Uses2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been used for the visual sensing of melamine (at parts-per-billion (ppb) level) by a highly sensitive analytical method based on Au nanoparticles.
DefinitionChEBI: Uracil-5-carboxylic acid is a pyrimidinemonocarboxylic acid that is uracil carrying a carboxy group at position 5. It is functionally related to a uracil. It is a conjugate acid of a uracil-5-carboxylate. It is a tautomer of a 2,4-dihydroxypyrimidine-5-carboxylic acid.
General Description2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. It has been used to synthesize N1-alkylated uracil derivatives.
6-(HYDROXYMETHYL)URACIL Polyoxin D zinc salt 2,4-DIHYDROXYPYRIMIDINE-5-CARBOXYLIC ACID MONOHYDRATE,2,4-DIHYDROXYPYRIMIDINE-5-CARBOXYLIC ACID HYDRATE RARECHEM AL BO 0778 6-AMINO-1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID 6-AMINO-1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID METHYL ESTER URACIL Ethyl 2-(Chlorosulfonyl)acetate methyl 6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate Ascoric Acid DIHYDROXY BENZALDEHYDE RARECHEM AL BO 1843 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL 6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5
-pyrimidinecarboxylic acid ethyl ester RARECHEM AL BO 1791 CARBOXYLIC ACID RARECHEM AL BO 1798 Uracil 5-carboxylic acid
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