ChemicalBook Product Catalog Analytical Chemistry Standard Standard Substance 1-(3-Chlorophenyl)piperazine hydrochloride

1-(3-Chlorophenyl)piperazine hydrochloride

1-(3-Chlorophenyl)piperazine hydrochloride Basic information
Product Name:1-(3-Chlorophenyl)piperazine hydrochloride
Synonyms:1-(3-CHLOROPHENYL)PIPERAZINE 2HCL;1-(3-Chlorophenyl)piperazine hydrochloride,97%;N-(3-Chlorophenyl) Piperazine HCl;1-(3-Chlorophenyl)piperazine hydrochloride;1-(3-CHLOROPHENYL)-PIPERAZINE HCL (MCLPPB);Piperazine, 1-(3-chlorophenyl)-, hydrochloride;1-(3-Chlorophenyl)piperidine/hydrochloric acid,(1:x);1-(3-Chlorophenyl)piperazine hydrochloride ,98%
CAS:65369-76-8
MF:C10H14Cl2N2
MW:233.14
EINECS:265-718-0
Product Categories:Serotonin receptor;Piperazines;API intermediates
Mol File:65369-76-8.mol
1-(3-Chlorophenyl)piperazine hydrochloride Structure
1-(3-Chlorophenyl)piperazine hydrochloride Chemical Properties
Melting point 210-214 °C (dec.)(lit.)
density 1,193g/cm
refractive index 1,598-1,600
Fp 9℃
storage temp. Store at RT
solubility methanol: soluble
form Solid
color Pale brown
Stability:Hygroscopic
CAS DataBase Reference65369-76-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn,T,F
Risk Statements 36/37/38-22-39/23/24/25-23/24/25-11
Safety Statements 26-36-24/25-45-36/37-16-7
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 3
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
1-(m-Chlorophenyl)piperazine hydrochloride English
SigmaAldrich English
1-(3-Chlorophenyl)piperazine hydrochloride Usage And Synthesis
Chemical PropertiesOff-white solid
UsesChlorophenyl Piperazine Hydrochloride Salt is a useful intermediate for organic synthesis and other chemical properties. Trazodone impurity.
General Description1-(3-Chlorophenyl)-piperazine, also known as meta-chlorophenylpiperazine or mCPP, is a designer drug analog of aryl-substituted piperazines. A stimulant, serotonin antagonist and reuptake inhibitor (SARU), mCPP can also be detected as a primary urinary metabolite of the antidepressant drug trazadone. This certified solution standard is suitable for use in piperazine testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.
Biological Activity5-HT 2C/2B receptor agonist/partial agonist; displays some activity at 5-HT 2A and 5-HT 1 receptors. pEC 50 values are 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT 2C , 2B and 2A , bovine 5-HT 1A and rat 5-HT 1B receptors respectively. Suppresses locomotor activity in rats in vivo .
1-(3-Chlorophenyl)piperazine hydrochloride Preparation Products And Raw materials
2-[4-(3,4-DICHLOROPHENYL)PIPERAZINO]QUINOXALINE 1-(3-Chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride 1-(2,3-Dichlorophenyl)piperazine hydrochloride 2-[4-(3,4-DICHLOROPHENYL)PIPERAZINO]-2-METHYLPROPANENITRILE 2-[4-(3,4-DICHLOROPHENYL)PIPERAZINO]-2-METHYLPROPANAMIDE 1-(3-Chlorophenyl)piperazine dihydrochloride 1-(3-Chlorophenyl)piperazine hydrochloride 4-AMINO-4-[4-(3,4-DICHLOROPHENYL)PIPERAZINO]-1,3-BUTADIENE-1,1,3-TRICARBONITRILE Topotecan hydrochloride 1-[4-(3-CHLOROPHENYL)PIPERAZINO]-3-[(4-CHLOROPHENYL)SULFANYL]-2-PROPANOL 1-(3,5-DICHLORO-4-METHOXYPHENYL)PIPERAZINE HYDROCHLORIDE 2-[[4-(3,4-DICHLOROPHENYL)PIPERAZINO](DIMETHYLAMINO)METHYLENE]MALONONITRILE 1-AMINO-4-(3,5-DICHLOROPHENYL)PIPERAZINE-2,5-DIONE 1-BENZYL-4-(2,3-DICHLORO-6-NITROPHENYL)PIPERAZINE 1-Phenyl-2-nitropropene 2-[4-(3-CHLOROPHENYL)PIPERAZINO]-1-PHENYL-1-ETHANONE O-(4-CHLOROBENZYL)OXIME CHLOROPHENYLSILANE 97 1-(3,5-DICHLOROPHENYL)PIPERAZINE
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