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Methotrexate α-Methyl Ester

Methotrexate α-Methyl Ester Basic information
Product Name:Methotrexate α-Methyl Ester
Synonyms:Methotrexate α-Methyl Ester;JYFDQHNTJJOKAS-AWEZNQCLSA-N;Methotrexate EP Impurity I;Methotrexate Impurity 9(EP-I);Methotrexate α-Methyl Ester (Impurity I);Methotrexate EP Impurity I（Amethopterin EP Impurity I）;(4S)-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid;Methotrexate EP Impurity I/Methotrexate 1-Methyl Ester/Methotrexate α-Methyl Ester/(4S)-4-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid
CAS:66147-29-3
MF:C21H24N8O5
MW:468.47
EINECS:
Product Categories:Aromatics, Chiral Reagents, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:66147-29-3.mol
Methotrexate α-Methyl Ester Structure
Methotrexate α-Methyl Ester Chemical Properties
solubility Aqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
form Solid
color Light Yellow to Dark Orange
Safety Information
MSDS Information
Methotrexate α-Methyl Ester Usage And Synthesis
UsesMethotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
Methotrexate α-Methyl Ester Preparation Products And Raw materials
METHOTREXATE-D3 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid 7-HYDROXY METHOTREXATE Methotrexate L-Glutamic acid der. METHOTREXATE DIMETHYL ESTER L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- L-Glutamic acid, N-[N-[N-[N-[4-[[(2, 4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-.gamma.-gluta myl]-L-.gamma.-glutamyl]-L-.gamma.-glutamyl]- 2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE N-(4-(METHYLAMINO)BENZOYL)-L-GLUTAMIC ACID Methotrexate impurity methotrexate-gamma-dimethylamide Methotrexate γ-Methyl Ester Aminopterin Methotrexate Related Compound E (50 mg) (4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid, hemihydrochloride) L-Glutamic acid, N-(N-(4-(((2,4-diamino-6-pteridinyl)methyl)methyl- D(-)-AMETHOPTERIN
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