5-Aminofluorescein

5-Aminofluorescein Basic information
Product Name:5-Aminofluorescein
Synonyms:5-Amino-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one Fluoresceinamine;5-amino-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;FLUORESCEINAMINE;FLUORESCEINAMINE ISOMER I;FLUORESCEINAMINE, ISOMER 1;5-amino-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid;5-AMINO-3',6'-DIHYDROXYSPIRO[ISOBENZOFURAN-1(3H),9'-(9H)XANTHEN]-3-ONE;5-AMINOFLUORESCEIN ISOMER I
CAS:3326-34-9
MF:C20H13NO5
MW:347.32
EINECS:222-043-6
Product Categories:marker;Fluorescent Labels and Indicators;Fluorescent Labels & Indicators
Mol File:3326-34-9.mol
5-Aminofluorescein Structure
5-Aminofluorescein Chemical Properties
Melting point 223 °C (dec.)(lit.)
Boiling point 481.89°C (rough estimate)
density 1.3724 (rough estimate)
refractive index 1.5180 (estimate)
storage temp. room temp
solubility DMF: 5 mg/ml; DMSO: 5 mg/ml
pka9.34±0.20(Predicted)
form powder
color red-brown
Water Solubility Soluble in water (partly), methanol (10 mg/ml), and acetone.
BRN 48395
Stability:Light and Moisture Sensitive
InChIKeyGZAJOEGTZDUSKS-UHFFFAOYSA-N
CAS DataBase Reference3326-34-9(CAS DataBase Reference)
EPA Substance Registry SystemSpiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 5-amino-3',6'-dihydroxy- (3326-34-9)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26
WGK Germany 3
10
TSCA Yes
HS Code 32049090
MSDS Information
5-Aminofluorescein Usage And Synthesis
Chemical PropertiesDark Red Solid
UsesGlycosaminoglycuronans react with 5-aminofluorescein to yield fluorescent derivatives. 5-aminofluorescein is also used to prepare FITC Isomer I (F-011, F-020).
Uses5-aminofluorescein is also used to prepare FITC Isomer I (CDX-F0011, CDX-F0020). It is a chemical used as molecular probe and important as fluorescent dye and for derivatives. Fluorescent labeling reagent for proteins. Used in the fluorescent antibody technique for rapid identification of pathogens.
DefinitionChEBI: 5-aminofluorescein is a primary amino compound that is fluorescein carrying an amino substituent at C-5. Building block/intermediate for the synthesis of the fluorescent dye flourescein; also used to produce N-(fluorescein-5-yl)maleamic acid. It derives from a fluorescein (lactone form).
General DescriptionFluoresceinamine, isomer I belongs to the class of derivatized fluoresceins.
5-Aminofluorescein Preparation Products And Raw materials
Raw materialsSodium sulfide-->Resorcinol-->Sodium hydrosulfide-->4-Nitrophthalic acid-->4-AMINO-N-METHYLPHTHALIMIDE-->6-Aminofluorescein
Preparation ProductsFluorescein isothiocyanate-->azidofluorescein
Fluorescein Sodium EC 1.14.14.3 4-AMINOFLUORESCEIN DIACETATE,4-AMINOFLUORESCEIN DIACETATE Fluorescein isothiocyanate 5-Aminofluorescein ALTRENOGEST 6-Aminocaproic acid Fluorescein diacetate Glycine 5-(((2-(carbohydrazino)methyl)thio)acetyl)aminofluorescein aminooxyacetyl hydrazide N-(2-aminoethylcarbonyl)-5(6)-aminofluorescein,N-(2-aminoethylcarbonyl)-5(6)-aminofluorescein Fluorescein Tris(hydroxymethyl)aminomethane AMINO ACIDS CHLOROPHOSPHONAZO III BENZOICACID 5-(((2-(CARBOHYDRAZINO)METHYL)THIO)ACETYL)AMINOFLUORESCEIN,5-(((2-(CARBOHYDRAZINO)METHYL)THIO)ACETYL)AMINOFLUORESCEIN (hexadecanoyl)aminofluorescei

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