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| | IOMEPROL Basic information |
| Product Name: | IOMEPROL | | Synonyms: | N1,N3-bis(2,3-dihydroxypropyl)-5-(2-hydroxy-N-methylacetamido)-2,4,6-triiodoisophthalamide;IOMEPROL;1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)methylamino]-2,4,6-triiodo-;Imeron;Iomeron 350;Iomeron;N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)methylamino]-2,4,6-triiodo-1,3-benzenedicarboxamide;N,N'-Bis(2,3-dihydroxypropyl)-5-[methyl(hydroxyacetyl)amino]-2,4,6-triiodoisophthalamide | | CAS: | 78649-41-9 | | MF: | C17H22I3N3O8 | | MW: | 777.09 | | EINECS: | 1533716-785-6 | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;pharmacetical | | Mol File: | 78649-41-9.mol |  |
| | IOMEPROL Chemical Properties |
| Toxicity | LD50 (400 mgI/ml soln) i.v. in mice, rats (gI/kg): 19.9, 14.5; LD50 (370 mgI/ml soln) i.v. in dogs (gI/kg): >12.5 (Morisetti) |
| | IOMEPROL Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Diagnostic aid (radiopaque medium). | | Definition | ChEBI: A benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a glycoloyl(methyl)amino group at the 5-position. | | Hazard | Low toxicity. |
| | IOMEPROL Preparation Products And Raw materials |
| Raw materials | 5-AMino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxaMide Tetraacetate-->5-Amino-2,4,6-triiodisophthaloyl acid dichloride-->5-Amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide-->N-DesMethyl IoMeprol-->5-[[2-(Acetyloxy)acetyl]amino]-2,4,6-triiodo-1,3-benzenedicarbonyl Dichloride-->5-Aminoisophthalic acid-->Dimethyl sulfate-->Iodomethane |
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