Betaxolol hydrochloride

Betaxolol hydrochloride Basic information
Product Name:Betaxolol hydrochloride
Synonyms:1-[4-[2-(CYCLOPROPYLMETHOXY)ETHYL]PHENOXY]-3-ISOPROPYLAMINO-2-PROPANOL HYDROCHLORIDE;BETAXOLOL CHLOROHYDRATE;BETAXOLOL HCL;BETAXOLOL HYDROCHLORIDE;BETAXOLOL HYDROCHLORIDE MONOHYDRATE;SL 75212;(+-)-1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)-2-propano;1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-isopropylaminopropan-2-olhydroc
CAS:63659-19-8
MF:C18H30ClNO3
MW:343.89
EINECS:264-384-3
Product Categories:Cardiovascular;Adrenoceptor
Mol File:63659-19-8.mol
Betaxolol hydrochloride Structure
Betaxolol hydrochloride Chemical Properties
Melting point 116°
storage temp. 2-8°C
solubility H2O: 36 mg/mL, soluble
form solid
color white
Water Solubility Soluble to 50 mM in water
Merck 14,1182
Stability:Hygroscopic
CAS DataBase Reference63659-19-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22
WGK Germany 3
RTECS UA9823000
HS Code 2922504500
ToxicityLD50 in mice (mg/kg): 944 orally; 37 i.v. (Manoury)
MSDS Information
ProviderLanguage
SigmaAldrich English
Betaxolol hydrochloride Usage And Synthesis
DescriptionBetaxolol hydrochloride is a cardioselective β-adrenergic blocker, reportedly devoid of intrinsic sympathomimetic and membrane stabilizing properties. Its long duration of action permits once-daily dosing in mild to moderate hypertension. It is also being evaluated in glaucoma.
DescriptionBetaxolol (hydrochloride) (Item No. 26285) is an analytical reference standard categorized as a β1-adrenergic receptor antagonist. Formulations containing β-adrenergic receptor antagonists have been used to enhance physical performance in athletes. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .
Chemical PropertiesWhite or almost white, crystalline powder.
OriginatorSynthelabo (France)
UsesBetaxolol Hydrochloride, a cardioselective β1-adrenergic blocker. An antihypertensive; antiglaucoma.
Usesantifungal
DefinitionChEBI: The hydrochloride salt of betaxolol.
Brand nameBetoptic (Alcon); Kerlone (Sanofi Aventis).
Biological ActivitySelective β 1 -adrenoceptor antagonist.
storageStore at RT
Betaxolol hydrochloride Preparation Products And Raw materials
Betaxolol Trinexapac-ethyl Betaxolol hydrochloride Sibutramine hydrochloride Tramadol hydrochloride O-Desmethyl Metoprolol 4-Methoxyphenylacetone Anisole 4-Methoxyphenylacetic acid Ethylparaben (Trifluoromethoxy)benzene 3-(METHOXYMETHOXY)BENZALDEHYDE ISOXADIFEN-ETHYL 3-(4-methylphenoxy)propan-1-amine Ethyl acetate p-Anisaldehyde Diphenhydramine Hydrochloride Ethyl acrylate Betaxolol Hcl

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