10E,12Z-octadecadienoic acid

10E,12Z-octadecadienoic acid Basic information
Product Name:10E,12Z-octadecadienoic acid
Synonyms:LINOLEIC ACID (10-TRANS, 12-CIS);DELTA 10 TRANS DELTA 12 CIS OCTADECADIENOIC ACID;CONJUGATED LINOLEIC ACID (10E,12Z);CONJUGATED (10E,12Z)-LINOLEIC ACID;CLA 10TR,12C;10E,Z12-CLA;(10E,12Z)-10,12-OCTADECADIENOIC ACID;10E,12Z-CLA
CAS:2420-56-6
MF:C18H32O2
MW:280.45
EINECS:607-342-5
Product Categories:
Mol File:2420-56-6.mol
10E,12Z-octadecadienoic acid Structure
10E,12Z-octadecadienoic acid Chemical Properties
Boiling point 377.7±11.0 °C(Predicted)
density 0.911±0.06 g/cm3(Predicted)
Fp 14℃
storage temp. −20°C
solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO, Methanol (Slightly)
pka4.78±0.10(Predicted)
form Oil
color Colourless
Stability:Light Sensitive
Safety Information
Hazard Codes F,T
Risk Statements 11-23/24/25-39/23/24/25
Safety Statements 16-36/37-45
RIDADR UN 1170 3/PG 2 -Ethanol,solution
MSDS Information
10E,12Z-octadecadienoic acid Usage And Synthesis
DescriptionConjugated linoleic acid (CLA) refers to a family of 8 geometric isomers of linoleic acid in which the two double bonds are contiguous. (The predominant form of linoleic acid in nature, 18:ω6, has double bonds at 9 and 12, interrupted by a methylene carbon.) CLA is found in both meat and dairy products, but it is not found to any significant degree in plants. The predominant isomer of CLA in animal tissue is 9Z,11E; smaller amounts of 10E,12Z also occur. Various antioxidant and antitumor activities have been attributed to CLA or its downstream metabolites. Reported health benefits of dietary supplementation with CLA have been attributed variously to competitive inhibition of Δ6-desaturase and/or PPARγ activation. [Matreya, LLC. Catalog No. 1249]
Uses10-trans,12-cis-Linoleic Acid?is an isomer of Linoleic Acid (L467495). Linoleic Acid is a dietary unsaturated fatty acid, which increases the expression of adhesion molecules and attenuates Endothelial cell function. Linoleic Acid is anti-inflammatory, acne reductive, and moisture retentive when applied topically on the skin. It is popular in the beauty products industry because of its beneficial properties on the skin.
DefinitionChEBI: (10E,12Z)-octadecadienoic acid is an octadeca-10,12-dienoic acid having (10E,12Z)-configuration. It is a conjugate acid of a (10E,12Z)-octadecadienoate.
10E,12Z-octadecadienoic acid Preparation Products And Raw materials
CLA?10tr,12c?Free?Fatty?Acid LinoleicAcid Calcium conjugated linoleic acid CLA?10tr,12c?Ethyl?Ester β-Estradiol CLA 9C,11TR TRIGLYCERIDE Ethyl 2-(Chlorosulfonyl)acetate Microencapsulated Conjugated linoleic acid 10E,12Z-octadecadienoic acid CLA?10tr,12c?Methyl?Ester? Ascoric Acid CLA 10TR,12C TRIGLYCERIDE Stearic acid Folic acid Linoleic acid Cojugated linoleic acid soft gels Methyl?9c,11tr-Octadecadienoate?9c Citric acid

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