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| | Droprenilamine Basic information |
| Product Name: | Droprenilamine | | Synonyms: | Droprenilamine;MG-8926;N-(3,3-Diphenylpropyl)-α-methylcyclohexaneethanamine;Valcor;droprenylamine;Benzenepropanamine, N-(2-cyclohexyl-1-methylethyl)-γ-phenyl-;Droprenilamine USP/EP/BP | | CAS: | 57653-27-7 | | MF: | C24H33N | | MW: | 335.532 | | EINECS: | | | Product Categories: | | | Mol File: | 57653-27-7.mol |  |
| | Droprenilamine Chemical Properties |
| Boiling point | 466.0±34.0 °C(Predicted) | | density | 0.975±0.06 g/cm3(Predicted) | | pka | 10.52±0.29(Predicted) |
| | Droprenilamine Usage And Synthesis |
| Originator | Valcor,Maggioni,Italy,1979 | | Uses | Vasodilator (coronary). | | Definition | ChEBI: Droprenilamine is a diarylmethane. | | Manufacturing Process | The flask of a Parr hydrogenation apparatus was charged with 10.5 g of 3,3-diphenylpropylamine, 7.7 g of cyclohexylacetone, 50 ml methanol and 150 mg
of platinum dioxide. Hydrogen at a pressure of 3 atmospheres was introduced
and the mixture stirred. Upon absorption of the theoretical amount of
hydrogen, stirring is discontinued, the catalyst is filtered off and the solution
is evaporated to dryness. The residue is taken up with ether and the
hydrochloride is precipitated with HCl in alcoholic solution. The product, as
collected on a filter and washed with ether, is recrystallized from isopropanol.
Yield: 17 g (92.5% of theory). MP: 175°C to 177°C. | | Brand name | Valcor (Maggioni Farmaceutici S.p.A., Italy). | | Therapeutic Function | Coronary vasodilator |
| | Droprenilamine Preparation Products And Raw materials |
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