Cefuzonam

Cefuzonam Basic information
Product Name:Cefuzonam
Synonyms:CEFUZONAM;(6r,7s)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-8-oxo-3-(thiadiazol-5-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-8-oxo-3-[(5-thiadiazolylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cefuzonam sodium;1-[[(6r,7r)-7-[[(2z)-(5-amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-imidazo[1,2-b]pyridazinium hydroxide inner salt;CL-251931;CZON;L-105【Cephem antibiotic】
CAS:82219-78-1
MF:C16H15N7O5S4
MW:513.59
EINECS:
Product Categories:
Mol File:82219-78-1.mol
Cefuzonam Structure
Cefuzonam Chemical Properties
density 1.97±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka2?+-.0.50(Predicted)
CAS DataBase Reference82219-78-1(CAS DataBase Reference)
Safety Information
ToxicityLD50 in female, male mice, female, male rats (mg/kg): 4117, >4800, 4281, 4222 i.v.; 6424, 6783, >8000, >8000 i.p.; all >10000 orally (Takita)
MSDS Information
Cefuzonam Usage And Synthesis
DescriptionCefuzonam is an injectable cephalosporin reported to be active against a large percentage of Gram-negative bacteria and some Gram-positive bacteria, including those resistant to other third-generation cephdosporins.
OriginatorLederle (USA)
DefinitionChEBI: A second generation cephalosporin antibiotic.
Brand nameCosmosin
Cefuzonam Preparation Products And Raw materials
Raw materialsMagnesium sulfate-->Triethylamine-->Sodium bicarbonate-->Phosphorus pentachloride-->Activated carbon,decolor
sodium (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl] amino]-8-oxo-3-(thiadiazol-5-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2 .0]oct-2-ene-2-carboxylate Methylisothiazolinone Betaine KP 736 Ceftezole sodium 2-Mercapto-5-methyl-1,3,4-thiadiazole Ceftizoxime Benzothiazole Cefuzonam Acetyl chloride KP 736 Glycine Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Ceftezole 2,1,3-Benzothiadiazole 2,2'-Dithiobis(benzothiazole) Ceftizoxime sodium Cefmetazole

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