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| | Sennoside B Basic information |
| Product Name: | Sennoside B | | Synonyms: | PURSENNIDE;SENNOSIDE B 96.5+%;Sennoside B std.;9,9-Bianthracene-2,2-dicarboxylic acid, 5,5-bis(.beta.-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-, (9R,9S)-;(9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid;SENNIDINE B(RG);SENNOSIDE B(P);SENNOSIDE B(SH) | | CAS: | 128-57-4 | | MF: | C42H38O20 | | MW: | 862.74 | | EINECS: | 204-895-0 | | Product Categories: | The group of Sennosides;Anthraquinones, Hydroquinones and Quinones;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors | | Mol File: | 128-57-4.mol |  |
| | Sennoside B Chemical Properties |
| Melting point | 209～212℃ | | alpha | D20 -100° (c = 0.2 in 70% acetone); D20 -67° (c = 0.4 in 70% dioxane) | | Boiling point | 698.48°C (rough estimate) | | density | 1.3066 (rough estimate) | | refractive index | 1.7630 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO (Very Slightly, Heated), Methanol (Slightly, Heated) | | form | neat | | pka | 3.31±0.40(Predicted) | | color | Light Yellow to Dark Yellow | | BRN | 5723747 | | Stability: | Hygroscopic | | LogP | 1.880 (est) | | CAS DataBase Reference | 128-57-4(CAS DataBase Reference) |
| Risk Statements | 22 | | Safety Statements | 22-45-24/25 | | WGK Germany | 3 | | HS Code | 29329990 |
| | Sennoside B Usage And Synthesis |
| Chemical Properties | White to brown powder | | Uses | Sennoside B is used in the inhibition of platelet driven growth factor (PDGF) used and may inhibit proliferative disease which depend upon the PDGF pathway. Laxative. | | Definition | ChEBI: A member of the class of sennosides that is (9R,9'S)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D
glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'. | | Purification Methods | Sennoside B forms yellow crystals from aqueous acetone or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3402.] |
| | Sennoside B Preparation Products And Raw materials |
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