O-DESMETHYLNAPROXEN

O-DESMETHYLNAPROXEN Basic information
Product Name:O-DESMETHYLNAPROXEN
Synonyms:Naproxen Impurity 1(Naproxen EP Impurity A);(s)-6-hydroxy-α-methyl-2-naphthaleneacetic acid;(aS)-6-Hydroxy-α-methyl-2-naphthaleneacetic Acid;(S)-2-(6-Hydroxy-2-naphthyl)propionic Acid;(S)-6-Demethylnaproxen;(S)-6-O-Desmethylnaproxen;(S)-O-Desmethyl Naproxen;(aS)-6-Hydroxy-a-methyl-2-naphthaleneacetic Acid
CAS:52079-10-4
MF:C13H12O3
MW:216.23
EINECS:
Product Categories:Intermediates & Fine Chemicals;Metabolites & Impurities;Chiral Reagents;Pharmaceuticals
Mol File:52079-10-4.mol
O-DESMETHYLNAPROXEN Structure
O-DESMETHYLNAPROXEN Chemical Properties
Melting point 182-183 °C
Boiling point 432.1±20.0 °C(Predicted)
density 1.297±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble
pka4.87±0.30(Predicted)
form neat
color white
BRN 8838512
CAS DataBase Reference52079-10-4
Safety Information
Hazard Codes Xn,N
Risk Statements 22-43-50/53
Safety Statements 36/37-60-61
RIDADR UN 3077 9/PG 3
WGK Germany 3
MSDS Information
O-DESMETHYLNAPROXEN Usage And Synthesis
Chemical PropertiesOff-Whie to Pale Pink Solid
UsesA metabolite of Naproxen
UsesO-Desmethylnaproxen can be used for assaying naproxen metabolites.
DefinitionChEBI: A member of the class of naphthols that is naproxen in which the 6-methoxy group has been demethylated.
Biochem/physiol ActionsCYP2C9 metabolite of naproxen
O-DESMETHYLNAPROXEN Preparation Products And Raw materials
Naproxen sodium Naproxen

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