4-BROMO-2,6-DIFLUOROBENZYL ALCOHOL

4-BROMO-2,6-DIFLUOROBENZYL ALCOHOL Basic information
Product Name:4-BROMO-2,6-DIFLUOROBENZYL ALCOHOL
Synonyms:4-BROMO-2,6-DIFLUOROBENZYL ALCOHOL;RARECHEM AL BD 1306;2,6-DIFLUORO-4-BROMOBENZYLALCOHOL;4-bromo-2,6-difluoro-benzenemethanol;4-bromo-2,6-difluorobenzyl;(4-BROMO-2,6-DIFLUOROPHENYL)METHANOL;Benzenemethanol, 4-bromo-2,6-difluoro-
CAS:162744-59-4
MF:C7H5BrF2O
MW:223.01
EINECS:627-656-6
Product Categories:Pharmaceutical intermediate;Benzhydrols, Benzyl & Special Alcohols;Alcohol;Miscellaneous;Alcohols;C7 to C8;Oxygen Compounds
Mol File:162744-59-4.mol
4-BROMO-2,6-DIFLUOROBENZYL ALCOHOL Structure
4-BROMO-2,6-DIFLUOROBENZYL ALCOHOL Chemical Properties
Melting point 76-81 °C (lit.)
Boiling point 250℃
density 1.744
Fp 105℃
storage temp. Sealed in dry,Room Temperature
pka13.21±0.10(Predicted)
form Solid
color White to Light yellow
InChIKeyLSRHFWSNUFIKER-UHFFFAOYSA-N
CAS DataBase Reference162744-59-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
Hazard Note Irritant
HS Code 2906290090
MSDS Information
ProviderLanguage
SigmaAldrich English
4-BROMO-2,6-DIFLUOROBENZYL ALCOHOL Usage And Synthesis
Uses

4-Bromo-2,6-difluorobenzyl alcohol is an organic intermediate. It has been reported that 4-bromo-2,6-difluorobenzyl alcohol can be used to prepare RET inhibitors.

Application4-Bromo-2,6-difluorobenzyl alcohol can be used to prepare RET inhibitors.
Preparation

4-Bromo-2,6-difluorobenzyl alcohol can be obtained by reducing the carboxyl group from 4-bromo-3,5-difluorobenzoic acid.

2-Bromoethanol 6-BROMO-2,3-DIFLUOROBENZYL ALCOHOL 4-Bromo-2,6-difluorobenzoic acid RARECHEM AL BI 1306 RARECHEM AL BP 1308 4-BROMO-2,6-DIFLUOROBENZYL ALCOHOL 4-BROMO-2,3,6-TRIFLUOROBENZYL ALCOHOL ethyl 4-bromo-2,3,5,6-tetrafluorobenzimidate RARECHEM AL BE 1308 TERT-BUTYL 4-BROMO-2,6-DIFLUOROBENZOATE 4-BROMO-2,3,5,6-TETRAFLUOROBENZYLALCOHOL Methyl 4-bromo-2,6-difluorobenzoate RARECHEM AL BI 1308 RARECHEM AL BF 1308 RARECHEM AL BP 1306 2,6-Difluorobenzyl alcohol TERT-BUTYL 4-BROMO-2,3,5,6-TETRAFLUOROBENZOATE 4-BROMO-2,3,5,6-TETRAFLUOROBENZOIC ACID

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