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| | Sitagliptin Impurity 12 Basic information |
| Product Name: | Sitagliptin Impurity 12 | | Synonyms: | (Z)-1-(3-(trifluoromethyl);2-Buten-1-one, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)-;Sitagliptin EP Impurity 12 | | CAS: | 1803026-54-1 | | MF: | C16H12F6N4O | | MW: | 390.28 | | EINECS: | | | Product Categories: | | | Mol File: | 1803026-54-1.mol |  |
| | Sitagliptin Impurity 12 Chemical Properties |
| Boiling point | 517.5±60.0 °C(Predicted) | | density | 1.52±0.1 g/cm3(Predicted) | | solubility | soluble in Chloroform, DCM, Methanol | | pka | -0.06±0.20(Predicted) | | form | Oil | | color | Light Yellow |
| | Sitagliptin Impurity 12 Usage And Synthesis |
| Uses | (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985),an impurity of Sitagliptin (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. |
| | Sitagliptin Impurity 12 Preparation Products And Raw materials |
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