Sertaconazole nitrate

Sertaconazole nitrate Basic information
Product Name:Sertaconazole nitrate
Synonyms:NITRATE SERTACONAZOLE;1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole mononitrate;1-[2-[(7-Chlorobenzo[b]thien-3-yl)Methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-iMidazole Nitrate;DerMovit;Ertaczo;Sertaconazole Mononitrate;1H-Imidazole, 1-[2-[(7-chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1);SEROTONIN
CAS:99592-39-9
MF:C20H15Cl3N2OS.HNO3
MW:500.78
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Inhibitors
Mol File:99592-39-9.mol
Sertaconazole nitrate Structure
Sertaconazole nitrate Chemical Properties
Melting point 158-160°
storage temp. -20°C
solubility DMSO: soluble20mg/mL, clear
pkapKb: 7.26(at 25℃)
form powder
color white to beige
InChIKeyHAAITRDZHUANGT-UHFFFAOYSA-N
Safety Information
WGK Germany 3
MSDS Information
Sertaconazole nitrate Usage And Synthesis
DescriptionSertaconazole nitrate is a new broad spectrum imidazole antifungal agent introduced in a topical formulation for the treatment of cutaneous infections. Its mechanism of action is the inhibition of ergosterol synthesis and interference with the permeability of fungus cell membranes. An oral formulation is currently under investigation for the treatment of bucco-pharyngeal fungal infections.
Chemical PropertiesOff-White Solid
OriginatorFerrer (Spain)
UsesAn imidazole antifungal agent, inhibits the synthesis of ergosterol, an essential cell wall component of fungi.
UsesAntibacterial;ergosterol synthesis inhibitor
Brand nameDermofix; Zalain
Sertaconazole nitrate Preparation Products And Raw materials
Miconazole nitrate Econazole nitrate Sertaconazole nitrate Ethanol Guaiacol 4-Methoxybenzylchloride Methoxy 2-Methoxyethanol Anisole Ethylparaben (Trifluoromethoxy)benzene Sertaconazole nitrate p-Anisic acid p-Anisidine Diethyl ether Miconazole nitrate Ointment Ethyl acetate Fenticonazole nitrate

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