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| | CRF (HUMAN, RAT) Basic information |
| Product Name: | CRF (HUMAN, RAT) | | Synonyms: | CORTICOTROPIN RELEASING FACTOR;CORTICOTROPIN RELEASING FACTOR (CRF), HUMAN, RAT;CORTICOTROPIN RELEASING FACTOR, HUMAN;CORTICOTROPIN RELEASING FACTOR, HUMAN AND RAT;CORTICOTROPIN RELEASING FACTOR HUMAN, RAT;CRF, HUMAN AND RAT;CRF (HUMAN, RAT);CRH | | CAS: | 86784-80-7 | | MF: | C208H344N60O63S2 | | MW: | 4757.45 | | EINECS: | | | Product Categories: | proteins;Peptide;CRF receptor and related | | Mol File: | Mol File | ![CRF (HUMAN, RAT) Structure]() |
| | CRF (HUMAN, RAT) Chemical Properties |
| storage temp. | −20°C | | solubility | H2O : 16.66 mg/mL (3.50 mM; Need ultrasonic and warming) | | form | White to off-white lyophilized solid | | Water Solubility | Soluble to 1.10 mg/ml in water |
| WGK Germany | 3 | | RTECS | GM7925000 | | F | 10 | | HS Code | 2937190000 |
| | CRF (HUMAN, RAT) Usage And Synthesis |
| Uses | Treatment of symptoms associated with peritumoral edema in brain tumor patients. | | Uses | Corticotropin Releasing Factor human, rat has been used:
- as a component in Dulbecco′s modified eagle medium (DMEM) for incubating lung explants
- as a component in serum-free complete medium for isolation and culturing of fetal distal lung epithelial cells
- in the synthesis of the corticotropin-releasing factor(CRF)-TAMRA?1?mixture
- in chronic intracerebroventicular administration, to study its effect on hypoxia in hippocampus
| | Brand name | Xerecept (Hollister-Stier) [Note—The source of the product (human, porcine, etc.) must be indicated in the labeling.]. | | General Description | Corticotropin-releasing factor is a 41-amino-acid polypeptide. It is expressed in neurons, hypothalamus?and amygdala. | | Biochem/physiol Actions | CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress. | | storage | Store at -20°C |
| | CRF (HUMAN, RAT) Preparation Products And Raw materials |
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