|
| | Erythromycin ethylsuccinate Basic information |
| | Erythromycin ethylsuccinate Chemical Properties |
| Melting point | 219-224 C | | Boiling point | 778.19°C (rough estimate) | | density | 1.1417 (rough estimate) | | refractive index | 1.5280 (estimate) | | Fp | >110°(230°F) | | storage temp. | Sealed in dry,Room Temperature | | solubility | ethanol: soluble50mg/mL | | form | solid | | pka | 13.09±0.70(Predicted) | | color | white | | Water Solubility | Freely soluble in organic solvents, practically insoluble in water | | Stability: | Hygroscopic | | CAS DataBase Reference | 1264-62-6 |
| | Erythromycin ethylsuccinate Usage And Synthesis |
| Chemical Properties | ERYTHROMYCIN ETHYLSUCCINATE is crystals
| | Uses | A broad spectrum antibiotic commonly targeting bacteria responsible for respiratory tract infections | | Uses | antibacterial | | Definition | ChEBI: Erythromycin ethylsuccinate is a erythromycin derivative that is erythromycin A in which the hydroxy group at position 3R is substituted by a (4-ethoxy-4-oxobutanoyl)oxy group. It is used for the treatment of a wide variety of bacterial infections. It is a succinate ester, a cyclic ketone, an erythromycin derivative and an ethyl ester. It is functionally related to an erythromycin A. | | Brand name | E-Mycin (Pharmacia & Upjohn); E.E.S.
(Abbott); Eryped (Abbott); Pediamycin (Ross); Wyamycin
(Wyeth). | | General Description | Erythromycin ethylsuccinate (EES, Pediamycin, EryPed) isthe ethylsuccinate mixed ester of erythromycin in which the2＇-hydroxyl group of the desosamine is esterified. It isabsorbed as the ester and hydrolyzed slowly in the body toform erythromycin. It is somewhat acid labile, and itsabsorption is enhanced by the presence of food. The ester isinsoluble in water but soluble in alcohol and ether. |
| | Erythromycin ethylsuccinate Preparation Products And Raw materials |
|
