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Cabozantinib impurity 1DYH

Cabozantinib impurity 1DYH Basic information
Product Name:Cabozantinib impurity 1DYH
Synonyms:N-[4-[(6,7-Dimethoxy-1-oxido-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide;Cabozantinib impurity 1DYH;1,1-Cyclopropanedicarboxamide, N-[4-[(6,7-dimethoxy-1-oxido-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-;4-(4-(1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6,7-dimethoxyquinoline 1-oxide ;N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-6,7-dimethoxyquinolin-4-amine
CAS:1621681-63-7
MF:C28H24FN3O6
MW:517.51
EINECS:
Product Categories:
Mol File:1621681-63-7.mol
Cabozantinib impurity 1DYH Structure
Cabozantinib impurity 1DYH Chemical Properties
density 1.36±0.1 g/cm3(Predicted)
pka13.86±0.70(Predicted)
Safety Information
MSDS Information
Cabozantinib impurity 1DYH Usage And Synthesis
UsesCabozantinib N-oxide is a impurity of Cabozantinib (X745500), a medication used to treat medullary thyroid cancer. As well, it can be used in biological study. Computational network biological approach based on pathway cross-talk inhibition identified new synergistic drug combinations using raloxifene and cabozantinib for treatment of human breast cancer in xenograft mouse model. Potent c-MET inhibitor.
Cabozantinib impurity 1DYH Preparation Products And Raw materials
Cyclopropanecarboxylic acid, 1-[[(2-fluorophenyl)amino]carbonyl]- 1,1-Cyclopropanedicarboxamide, N,N'-bis[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]- Cabozantinib Malate Cyclopropanecarboxylic acid, 1-[(phenylaMino)carbonyl]- Quinoline, 6,7-dimethoxy-4-(4-nitrophenoxy)- 1,1-Cyclopropanedicarboxamide,N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl- N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluoro-3-hydroxyphenyl)-1,1-cyclopropanedicarboxamide Cyclopropanecarboxylic acid, 1-[[[4-[[7-methoxy-6-(sulfooxy)-4-quinolinyl]oxy]phenyl]amino]carbonyl]- Dasatinib 1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid LOXO-101 Cabozantinib impurity DX2 Cabozantinib Impurity EXA N,N'-Bis(4-hydroxyphenyl)hydrazine 1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl- N-(4-fluorophenyl)-N-(4-hydroxyphenyl)cyclopropane-1,1-dicarboxamide Cabozantinib Impurity DM Cabozantinib Impurity 5
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