ChemicalBook Product Catalog Biochemical Engineering Polypeptide H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH

H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH

H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH Basic information
Product Name:H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
Synonyms:Insulinotropin (human);Peptide GLP-1 (human glucose-lowering peptide-1);Glp-I (7-37);Glucagon like peptide I (7-37);Glucagon-related peptide (oncorhynchus kisutch), 3-L-glutamic acid-6-L-phenylalanine-9-L-aspartic acid-12-L-serine-15-L-glutamic acid-16-glycine-21-L-isoleucine-24-L-alanine-27-L-valine-28-L-lysine-31-glycine-;Tglp-1;GLP-1, 7-37;Preproglucagon 78-108
CAS:106612-94-6
MF:C151H228N40O47
MW:3355.67
EINECS:
Product Categories:peptides pharm;peptide
Mol File:106612-94-6.mol
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH Structure
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH Chemical Properties
density 1.48±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Water:30.0(Max Conc. mg/mL);8.34(Max Conc. mM)
form Lyophilized powder
Water Solubility Soluble in water at 2mg/ml
CAS DataBase Reference106612-94-6
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH Usage And Synthesis
UsesGlucagon-Like Peptide 1 Fragment 7-37 human has been used:
  • as a positive control for insulin secretion of pancreatic islets
  • to test its effect on insulin response in horse islets
  • in combination with mesenchymal stem cells (MSCs) test its protective effects in myocardial infarction

General DescriptionGlucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) is an amino-truncated form of GLP-1.
Biochem/physiol ActionsGlucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) interacts with the GLP-1 receptor (GLP-1r). It mediates insulin release by stimulating the cyclic AMP accumulation in islet cells GLP-l(7-37) is a potential therapeutic agent due to its insulin-secretagogue functionality.
storageStore at -20°C
H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH Preparation Products And Raw materials
Thymalfasin Eptifibatide Pralmorelin GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN Pramlintide acetate Triptorelin acetate Glucagon Thymopentin Growth hormone releasing peptide Nesiritide acetate Sermorelin H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH GLP-1（Glucagon-like peptide-1）(7-36) AC-LEU-VAL-LYS-ALDEHYDE GLP-2（Glucagon-like peptide-2） ([125I]-TYR)-GLP-1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) GLP-1 (9-36) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, PORCINE, RAT) GLP-1+ FITC（Glucagon-like peptide-1）(7-36)
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