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| | Cinnamamide Basic information |
| | Cinnamamide Chemical Properties |
| Melting point | 148-150 °C(lit.) | | Boiling point | 267.28°C (rough estimate) | | density | 1.1135 (rough estimate) | | refractive index | 1.5450 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 15?+-.0.50(Predicted) | | form | Crystalline Powder | | color | Off-white to beige | | BRN | 2040577 | | InChIKey | APEJMQOBVMLION-VOTSOKGWSA-N | | CAS DataBase Reference | 621-79-4(CAS DataBase Reference) | | NIST Chemistry Reference | Benzylidene acetamide(621-79-4) | | EPA Substance Registry System | 2-Propenamide, 3-phenyl- (621-79-4) |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 36 | | WGK Germany | 3 | | RTECS | GD6853000 | | TSCA | Yes | | HazardClass | IRRITANT | | HS Code | 29242990 |
| | Cinnamamide Usage And Synthesis |
| Chemical Properties | OFF-WHITE TO BEIGE CRYSTALLINE POWDER | | Uses | Cinnamamide, a non-lethal repellent, deters feeding by a wide range of avian species. | | Definition | ChEBI: The simplest member of the class of cinnamamides that consists of acrylamide bearing a phenyl substituent at the 3-position. | | Biological Activity | Cinnamamide is an amide form of of trans-cinnamic acid and a metabolite of Streptomyces. Cinnamamide exhibits low cytotoxicity against BEL-7402 human hepatoma cells and HT-1080 fibrosarcoma cells and inhibits cell growth (IC50s = 1.94 and 1.29 mM, respectively). In vivo, cinnamamide (40 and 100 mg/kg, i.p.) reduces tumor weight in a mouse model of C26 murine colon carcinoma. Cinnamamide (75 and 150 mg/kg, i.p.) also reduces tumor weight in a mouse model of murine hepatoma 22 by 42% and 49%, respectively, without reducing body weight when delivered one or three days following tumor implantation. When presented with cinnamamide-treated food at a concentration of 0.8% w/w, house and wood mice food consumption is reduced to 32% and 17% of pretreatment levels, respectively, however, wood mouse consumption returns to pretrial levels by day two. |
| | Cinnamamide Preparation Products And Raw materials |
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