Sineptina

Sineptina Basic information
Product Name:Sineptina
Synonyms:LEUCOMYCIN HYDRATE;KITASAMYCIN BASE;KITASAMYCIN;FORMACIDINE;ayermicina;2-[6-[[5-[(4,5-dihydroxy-4,6-dimethyl-2-oxanyl)oxy]-4-(dimethylamino)-3-hydroxy-6-methyl-2-oxanyl]oxy]-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde;Leucomycin complex;Kitasamycin Solution, 1000ppm
CAS:1392-21-8
MF:C35H59NO13
MW:701.84186
EINECS:232-429-6
Product Categories:
Mol File:1392-21-8.mol
Sineptina Structure
Sineptina Chemical Properties
Melting point 128-145 °C
storage temp. Sealed in dry,2-8°C
solubility ethanol: 50 mg/mL, clear to slightly hazy, light-yellow
form neat
color White to Off-White
Merck 14,5453
CAS DataBase Reference1392-21-8
Safety Information
Safety Statements 24/25
WGK Germany 1
RTECS WG9400000
10
HS Code 29419090
Toxicitymouse,LD50,intraperitoneal,1758mg/kg (1758mg/kg),Drugs in Japan Vol. -, Pg. 354, 1995.
MSDS Information
ProviderLanguage
SigmaAldrich English
Sineptina Usage And Synthesis
UsesSineptina is a family of closely related macrocyclic lactone antibiotics produced by Streptomyces kitasatoensis, discovered in 1953. The complex contained over 14 components with analogues A1, A4, A5, and A13 being the most abundant analogues.Sineptina is used as an animal health product for control of Gram positive bacteria, Gram negative cocci, leptospira and mycoplasma.
UsesLeucomycins (>85%) (cas# 1392-21-8) is a compound useful in organic synthesis.
DefinitionChEBI: Leucomycin V is a macrolide antibiotic produced by Streptomyces kitasatoensis, showing activity against a wide spectrum of pathogens. It has a role as a bacterial metabolite. It is a leucomycin and a macrolide antibiotic.
Pharmaceutical ApplicationsA naturally occurring product of Streptomyces kitasatoensis, available in Japan for parenteral and oral use, and as acetylkitasamycin for topical application. Elsewhere it is chiefly used in veterinary medicine.
Sineptina Preparation Products And Raw materials
Raw materialsStarch-->Butyl acetate
Preparation ProductsROKITAMYCIN
Aluminum acetylacetonate METHYL ISOCYANOACETATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) N-BUTYLISOCYANIDE PHENYLSELENOL Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) SALCOMINE 2,4-PENTANEDIONE, SILVER DERIVATIVE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Tosylmethyl isocyanide COBALT(II) ACETYLACETONATE Cupric acetylacetonate Ethyl isocyanoacetate TERT-BUTYL ISOCYANIDE Ferric acetylacetonate COBALT ETHYLENE DIAMINE CHLORIDE Benzyl isocyanide

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