HOE 140

HOE 140 Basic information
Product Name:HOE 140
Synonyms:RRP-(HYP)-G-(THI)-S-(D-TIC)-(OIC)-R;H-D-ARG-ARG-PRO-HYP-GLY-THI-SER-D-TIC-OIC-ARG-OH;H2N-D-ARG-ARG-PRO-HYP-GLY-THI-SER-D-TIC-OIC-ARG-OH;Icatibatide Acetate;Icatibant;D-Arg-[Hyp3,Thi5,D-Tic7,Oic8]bradykinin;D-Arg-L-Arg-L-Pro-L-t4Hyp-Gly-L-Thi-L-Ser-D-Tic-L-Oic-L-Arg-OH;H0E-140
CAS:130308-48-4
MF:C59H89N19O13S
MW:1304.52
EINECS:
Product Categories:peptide
Mol File:130308-48-4.mol
HOE 140 Structure
HOE 140 Chemical Properties
density 1.60±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Water:100.0(Max Conc. mg/mL);76.66(Max Conc. mM)
form powder
pka3.60±0.21(Predicted)
color white
Water Solubility Soluble to 1 mg/ml in water
CAS DataBase Reference130308-48-4
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
HOE 140 Usage And Synthesis
UsesAntagonist (bradykinin).
DefinitionChEBI: A ten-membered synthetic oligopeptide consisting of D-Arg, Arg, Pro, Hyp, Gly, Thi, Ser, D-Tic, Oic, and Arg residues joined in sequrence. A bradykinin receptor antagonist used as its acetate salt for the treatment of acut attacks of hereditary angioedema in adult patients.
Brand nameMetastat (CollaGenex).
storageStore at -20°C
HOE 140 Preparation Products And Raw materials
3-(3,4-DIHYDROISOQUINOLIN-2(1H)-YL)PROPAN-1-OL N-BENZYL-1-(1-PYRROLIDINYL)-2-PROPANAMINE HOE 140 Acetamide, N-(2-(nonylamino)ethyl)- N-(2-(BENZYLAMINO)ETHYL) CYCLOHEXANAMINE 2-Aminoethyldiisopropylamine 1-(3,4-dihydroisoquinolin-2(1H)-yl)propan-2-amine H-LEU-ARG-OH N2-BENZYL-N1,N1-DIETHYL-1,2-PROPANEDIAMINE 2-Amino-N-cyclohexylacetamide N-formylmethamphetamine 1,2,3,4-Tetrahydroisoquinoline-3-carboxamide (3R)-1-(2-AMINOETHYL)-3-PYRROLIDINOL METHYL-(2-THIOPHEN-2-YL-ETHYL)-AMINE 1-METHYL-2-THIOPHEN-2-YL-ETHYLAMINE N,N-DI-N-BUTYLETHYLENEDIAMINE (R)-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID AMIDE CHEMBRDG-BB 9070704

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