SCHRADAN

SCHRADAN Basic information
Product Name:SCHRADAN
Synonyms:schradan (bsi,iso,esa,jmaf);OMPA;OCTAMETHYLPYROPHOSPHORAMIDE;Octamethyl pyrophosphoramine;SCHRADAN;SCHADRAN;SCHRADEN;Recombinant Bacterial Outer Membrane Protein-A
CAS:152-16-9
MF:C8H24N4O3P2
MW:286.25
EINECS:205-801-0
Product Categories:proteins
Mol File:152-16-9.mol
SCHRADAN Structure
SCHRADAN Chemical Properties
Melting point 17℃
Boiling point bp0.5 120-125°; bp2.0 154°
density 1.24 g/cm3 (25 ºC)
refractive index 1.4698 (589.3 nm 20℃)
pka0.85±0.70(Predicted)
form liquid
color Viscous liquid
CAS DataBase Reference152-16-9
EPA Substance Registry SystemSchradan (152-16-9)
Safety Information
Hazard Codes T+
Risk Statements 27/28
Safety Statements 36/37-38-45
RIDADR 3018
HazardClass 6.1(a)
PackingGroup I
HS Code 29299090
Hazardous Substances Data152-16-9(Hazardous Substances Data)
ToxicityLD50 in male, female rats (mg/kg): 9.1, 42 orally; 15, 44 dermally (Gaines)
MSDS Information
SCHRADAN Usage And Synthesis
Chemical PropertiesOMPA is a colorless liquid in crude form; otherwise, it is a dark brown viscous liquid.
UsesInsecticide.
DefinitionChEBI: Schradan is a phosphorodiamide.
General DescriptionSchradan, octamethyl pyrophosphoramide(OMPA), bis[bisdimethylaminophosphonous] anhydride(Pestox III), is a viscous liquid that is miscible with waterand soluble in most organic solvents. It is not hydrolyzed byalkalies or water but is hydrolyzed by acids. Schradan isused as a systemic insecticide for plants, being absorbed bythe plants without appreciable injury. Insects feeding on theplant are incapacitated.
Schradan is a weak inhibitor of cholinesterases in vitro.In vivo, it is metabolized to the very strong inhibitor hydroxymethylOMPA. Hydroxymethyl OMPA is not stable andis metabolized further to the N-methoxide, which is a weakinhibitor of cholinesterase.
General DescriptionDark brown viscous liquid. Used as an insecticide and as an acaricide. Not registered as a pesticide in the U.S.
Reactivity ProfileOrganophosphates, such as SCHRADAN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Health HazardExtremely toxic; probable oral lethal dose in humans is 5-50 mg/kg, between 7 drops and 1 teaspoonful for a 150 lb. person. It is highly toxic when inhaled. Material is a cholinesterase inhibitor. It is similar in action to other organophosphorous pesticides in its toxicity. It is slightly less toxic than parathion. Gastrointestinal, neurologic and respiratory symptoms may accompany poisoning with SCHRADAN. High doses may cause a toxic psychosis similar to acute alcoholism. Persons taking phenobarbital and phenaglycodol together, glutethimide, chlorpromazine hydrochloride, or meprobamate may be at greater risk. These drugs appear to enhance the toxicity of the material markedly.
Fire HazardWhen heated to decomposition, SCHRADAN can emit highly toxic fumes of oxides of phosphorus. Decomposes when mixed with acid. Hydrolyzed under acid conditions to dimethylamine and orthophosphoric acid.
Safety ProfilePoison by ingestion, inhalation,skin contact, intraperitoneal, intravenous, subcutaneous,and ocular routes. Human systemic effects by ingestion: acholinesterase inhibitor. Has been found to inhibitperipheral cholinesterase without pronounced effects o
Potential ExposureMaterial is used as a systemic insecticide for plants and as an acaricide. Not registered as a pesticide in the United States.
ShippingUN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
IncompatibilitiesOrganophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides and active metals. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. Acids.
Waste DisposalIn accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.
SCHRADAN Preparation Products And Raw materials
Preparation ProductsDIMEFOX
SCHRADAN PHOSPHAMIDON

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