(R)-Amlodipine

(R)-Amlodipine Basic information
Product Name:(R)-Amlodipine
Synonyms:3-O-ethyl 5-O-methyl (4R)-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;Amlodipine Impurity 15(R-Isomer);d-Amlodipine,(R)-(+)-Amlodipine;(R)-(+)-Amlodipine;(R)-Amlodipine;3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4R)-;3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (R)-;d-Amlodipine
CAS:103129-81-3
MF:C20H25ClN2O5
MW:408.88
EINECS:
Product Categories:Amines;Chiral Reagents;Dihydropyridine;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:103129-81-3.mol
(R)-Amlodipine Structure
(R)-Amlodipine Chemical Properties
Melting point 101-103°C
Boiling point 527.2±50.0 °C(Predicted)
density 1.227±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka8.97±0.10(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
(R)-Amlodipine Usage And Synthesis
Chemical PropertiesWhite Solid
Uses(R)-Enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
Uses(R)-Enantiomer of Amlodipine. A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
DefinitionChEBI: (R)-amlodipine is the (4R)-enantiomer of amlodipine. It is an enantiomer of a (S)-amlodipine.
(R)-Amlodipine Preparation Products And Raw materials
Amlodipine Dimethyl Ester 3-ethyl 5-isopropyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Dehydro AMlodipine Oxalate 4-chloro-3-oxobutyric acid 2-[(2-AZIDOETHOXY)METHYL]-4-(2-CHLOROPHENYL)-3-ETHOXYCARBONYL-5-METHOXYCARBONYL)-6-METHYL-1,4-DIHYDROPYRIDINE Desmethyl amolodipine (S)-AMlodipine-d4 AMlodipine IMpurity F Maleate diethyl 4-(2-chlorophenyl)-2-((2-(1,3-dioxoisoindolin-2-yl)ethoxy)Methyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate Amlodipine Impurity 13 3,5-Pyridinedicarboxylicacid, 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester Amlodipine Impurity 25 Amlodipine Impurity 48 Amlodipine EP Impurity D Dimethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Amlodipine iMpurity K Amlodipine Impurity 10 Amlodipine N-Galactose

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