3,4-Difluorophenylboronic acid

3,4-Difluorophenylboronic acid Basic information
Product Name:3,4-Difluorophenylboronic acid
Synonyms:3,4-DIFLUOROBENZENE BORONIC ACID;3,4-DIFLUOROPHENYLBORONICACID;;3,4-Difluorophenylbo;3,4-Difluorophenylboronic acid, May contain varying amounts of anhydride, 97%;3,4-Difluorophenylboronic acid ,98%;3,4-Difluorophenylboronic acid,97%;dihydroxy(3,4-difluorophenyl)borane;3,4-DIFLUOROPHENYLBORONIC ACID FOR SYNTH;Boronic acid, B-(3,4-difluorophenyl)-
CAS:168267-41-2
MF:C6H5BF2O2
MW:157.91
EINECS:736-978-8
Product Categories:Boronic Acids;Boronic Acids;Boronic Acids and Derivatives;Substituted Boronic Acids;Boronic Acid;Aryl;Halogenated;Organoborons;HALIDE;blocks;BoronicAcids;FluoroCompounds;Fluorin-contained phenyl boronic acid series;Liquid crystal intermediates
Mol File:168267-41-2.mol
3,4-Difluorophenylboronic acid Structure
3,4-Difluorophenylboronic acid Chemical Properties
Melting point 305-310 °C (lit.)
Boiling point 265.4±50.0 °C(Predicted)
density 1.35±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
pka7.59±0.10(Predicted)
form Powder
color White
BRN 7369788
InChIKeyRMGYQBHKEWWTOY-UHFFFAOYSA-N
CAS DataBase Reference168267-41-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37/38-22
Safety Statements 37/39-26-36
WGK Germany 3
Hazard Note Irritant
HS Code 29319090
MSDS Information
ProviderLanguage
ACROS English
ALFA English
3,4-Difluorophenylboronic acid Usage And Synthesis
Chemical Propertieswhite powder
Usessuzuki reaction
UsesIntermediates of Liquid Crystals
Uses3,4-Difluorophenylboronic Acid is used as a building block in the synthesis of several organic compounds including that of substituted 6-phenylpurine bases and nucleosides via Suzuki-Miyaura cross-coupling reactions which show significant cytostatic activity in CCRF-CEM, HeLa, and L1210 cell lines. It is also used in the preparation of a potent cell penetrant Legumain inhibitor, 10t.
3,4-Difluorophenylboronic acid Preparation Products And Raw materials
Preparation Products(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid-->3',4'-Difluoro-biphenyl-4-ol-->3',4'-DIFLUORO-BIPHENYL-4-CARBOXYLIC ACID-->3-BIPHENYL-3',4'-DIFLUORO-ACETIC ACID -->2-(3,4-Difluoro-phenoxy)acetonitrile-->4-(2,4-Difluorophenyl)-3-methyl-2(5H)-furanone
3,4,5-TRIFLUOROPHENYLBORONIC ACID, PINACOL ESTER 4-CHLORO-2,6-DIFLUOROPHENYLBORONIC ACID 3,5-DIFLUOROPHENYLBORONIC ACID,3,5-DIFLUOROPHENYLBORONIC ACID 98%,3,5-Difluorophenylboronic Acid (contains varying amounts of Anhydride) 4,5-Difluoro-2-isopropoxyphenylboronic acid 2-BROMO-4,5-DIFLUOROPHENYLBORONIC ACID 4,5-DIFLUORO-2-METHOXYPHENYLBORONIC ACID 3,4-Difluoro-5-methoxybenzeneboronic acid 2,3,4-Trifluorophenylboronic acid 3,4-DIFLUORO-2-(BROMOMETHYL)PHENYL BORONIC ACID PINACOL ESTER 2-AMINO-4,5-DIFLUOROPHENYLBORONIC ACID 3,4-DIFLUORO-2-METHYLPHENYL BORONIC ACID PINACOL ESTER 4,5-DIFLUORO-2-ETHOXYPHENYLBORONIC ACID 4-CYANO-2,3-DIFLUOROPHENYLBORONIC ACID 3-AMINO-4,5-DIFLUOROPHENYLBORONIC ACID 3,4-DIFLUORO-5-NITROPHENYLBORONIC ACID 2-AMINO-3,4,5-TRIFLUOROPHENYLBORONIC ACID 2-BROMO-4,5-DIFLUOROPHENYLBORONIC ACID 3,4-DIFLUORO-5-(TRIFLUOROMETHYL)-PHENYLBORONIC ACID

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