ERIOCITRIN

ERIOCITRIN Basic information
Product Name:ERIOCITRIN
Synonyms:(S)-3',4',5,7-TETRAHYDROXYFLAVANONE-7-[6-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE];ERIOCITRIN;ERIODICTYL-7-RUTINOSIDE;ERIODICTYOL-7-O-RUTINOSIDE;ERIODICTYOL-7-RUTINOSIDE;(s)-3',4',5,7-tetrahydroxyflavanone-7-[6-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside];(2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxan-2-yl]oxy-chroman-4-one;ERIOCITRIN(SH)
CAS:13463-28-0
MF:C27H32O15
MW:596.53
EINECS:236-668-7
Product Categories:chemical reagent;pharmaceutical intermediate;Flavanones;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:13463-28-0.mol
ERIOCITRIN Structure
ERIOCITRIN Chemical Properties
Melting point 161-190°C
Boiling point 956.9±65.0 °C(Predicted)
density 1.77
storage temp. Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol
pka7.15±0.40(Predicted)
form neat
color Dark Beige to Very Dark Beige
BRN 1304401
LogP1.470 (est)
CAS DataBase Reference13463-28-0(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
10-21
HS Code 29389090
MSDS Information
ProviderLanguage
SigmaAldrich English
ERIOCITRIN Usage And Synthesis
DescriptionEriocitrin is a flavonoid originally isolated from lemon peel that has antioxidant and enzyme inhibitory activity. Eriocitrin inhibits lipid peroxidation in a cell-free assay when used at a concentration of 10 μM and enhances the effect of α-tocopherol on lipid peroxidation. It also decreases thiobarbituric acid reactive substances (TBARS) in rat plasma when administered at a dose of 75 μmol/kg, indicating a reduction in lipid peroxidation. Eriocitrin prevents acute exercise-induced increases in TBARS, Nε-(hexanoyl)lysine (HEL), o,o-dityrosine (DT), and nitrotyrosine (NT; ) in rat liver when administered at a dose of 600 mg/kg prior to exercise. It is also an inhibitor of monoamine oxidase A (MAO-A) and MAO-B (IC50s = 86.5 and 164 μM, respectively, for human recombinant receptors).
Chemical Propertiessolid
UsesEriocitrin is one of the main flavonoids in citrus limon byproduct dried powder (CBP) that exhibits antioxidant activity.
DefinitionChEBI: A disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage
targetLDL | ATP synthase
ERIOCITRIN Preparation Products And Raw materials
4-CHROMANONE SALOR-INT L498939-1EA L-LYXOSE MethylL-rhamnopyranoside Hesperidin PINOCEMBRIN 7-HYDROXYFLAVANONE 3'-HYDROXYFLAVANONE Butin Phloretin L-PICEIN 4'-ETHOXY-2'-METHOXY-ACETOPHENONE 4'-O-METHYLDAVIDIGENIN .beta.-D-Glucopyranoside, 4-methylphenyl 1,3-DI-N-PROPOXYBENZENE α-L-Rhamnopyranose monohydrate 4-ethoxypropiophenone 2',4'-DIHYDROXY-4-METHOXYDIHYDROCHALCONE

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