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| Product Name: | EPA | | Synonyms: | 5C,8C,11C,14C,17C-EICOSAPENTAENOIC ACID;5,8,11,14,17-EICOSAPENTAENOIC ACID;5Z,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID;ALL CIS-5,8,11,14,17-EICOSAPENTAENOIC ACID;ALL CIS 5-8-11-14-17 EPA;ALL CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID;C20:5 (ALL CIS-5,8,11,14,17) ACID;C20:5 OMEGA-3 | | CAS: | 73167-03-0 | | MF: | C20H29O2.Na | | MW: | 324.44 | | EINECS: | | | Product Categories: | Lipoxygenase (5-)Unsaturated fatty acids and derivatives;LipoxygenaseEnzyme Inhibitors by Enzyme;Omega 3 fatty acids and derivativesBiochemicals Found in Plants;Arachidonic Acid Cascade;Enzyme Inhibitors;L to;Lipids;Polyunsaturated | | Mol File: | 73167-03-0.mol |  |
| Melting point | −54-−53 °C(lit.) | | density | 0.943 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.4977(lit.) | | storage temp. | -20°C | | solubility | Ethanol: 1.5 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.5 mg/ml | | form | waxy solid | | color | white |
| Uses | reduces thromboxane A2 production and platelet aggregation, inhibits 5-lipoxygenase and prevents arteriosclerosis. | | Uses | cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:
- to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
- to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
- to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice
| | General Description | Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil. | | Biochem/physiol Actions | Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis. |
| | EPA Preparation Products And Raw materials |
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