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| | 2-Chlorobenzothiazole Basic information |
| | 2-Chlorobenzothiazole Chemical Properties |
| Melting point | 21-23 °C (lit.) | | Boiling point | 141 °C/30 mmHg (lit.) | | density | 1.303 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.637(lit.) | | Fp | >230 °F | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | -0.23±0.10(Predicted) | | form | Liquid | | color | Clear yellow to yellow-brownish | | Specific Gravity | 1.3711.303 | | Water Solubility | insoluble | | BRN | 116316 | | CAS DataBase Reference | 615-20-3(CAS DataBase Reference) | | NIST Chemistry Reference | Benzothiazole, 2-chloro-(615-20-3) | | EPA Substance Registry System | 2-Chlorobenzothiazole (615-20-3) |
| | 2-Chlorobenzothiazole Usage And Synthesis |
| Chemical Properties | CLEAR YELLOW TO YELLOW-BROWNISH LIQUID | | Uses | 2-Chloro-1,3-benzothiazole is used in the synthesis of CBTs which are good building blocks for bioluminescent compounds for imaging. | | Uses | 2-Chlorobenzothiazole was used in the synthesis of:
- (RS)- and (S)-lubeluzole
- (1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone derivatives
- 4H-thieno[2′,3′:4,5]pyrimido[2,1-b]benzothiazole derivatives
| | Purification Methods | It is purified by fractional distillation in vacuo. The 2-chloro-3-methylbenzothiazolinium 2,4-dinitrobenzenesulfonate crystallises from Ac2O, m 162-163o(dec). [Young & Amstutz J Am Chem Soc 73 4773 1951, Brower et al. J Org Chem 19 1830 1954, Hunter & Jones J Chem Soc 2190 1930, Beilstein 27 H 44, 27 II 18, 27 III/IV 1072.] |
| | 2-Chlorobenzothiazole Preparation Products And Raw materials |
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