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| | COLCHICOSIDE Basic information |
| | COLCHICOSIDE Chemical Properties |
| Melting point | 194-197°C | | Boiling point | 620.17°C (rough estimate) | | density | 1.3430 (rough estimate) | | refractive index | 1.6400 (estimate) | | storage temp. | Refrigerator | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | | form | A crystalline solid | | pka | 12.74±0.70(Predicted) |
| | COLCHICOSIDE Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Uses | A significantly toxic Colchicine analog with no anti-inflammatory properties. | | Definition | ChEBI: Colchicoside is a carbotricyclic compound, an alkaloid and a member of acetamides. | | Purification Methods | Purify colchicoside by chromatography through alumina and eluting with CHCl3, then recrystallising from Me2CO, m 275-280o (after releasing solvent at 180o). It also crystallises from EtOH; see colchicine. The tetraacetate has m 175-177o, [] D 15 -57o (c 1, CHCl3). [Bellet et al. Ann Pharm Fr 10 241 1952, Chem Abstr 47 3323 1953, Beilstein 14 IV 946 for colchicine.] |
| | COLCHICOSIDE Preparation Products And Raw materials |
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