ChemicalBook Product Catalog Chemical Reagents Organic reagents Cyanide / nitrile METHYLSULFONYLACETONITRILE

METHYLSULFONYLACETONITRILE

METHYLSULFONYLACETONITRILE Basic information
Product Name:METHYLSULFONYLACETONITRILE
Synonyms:2-(METHYLSULFONYL)ACETONITRILE;Methylsulphonylacetonitrile;mesylacetonitrile;2-(Methylsulphonyl)acetonitrile;Methanesulfonylacetonitrile,98+%;Methanesulphonylacetonitrile,98+%;Methylsulfonylacetonitrile, 98+%;Methylsufonylacetonitrile
CAS:2274-42-2
MF:C3H5NO2S
MW:119.14
EINECS:218-888-5
Product Categories:Aliphatics;C1 to C5;Cyanides/Nitriles;Nitrogen Compounds
Mol File:2274-42-2.mol
METHYLSULFONYLACETONITRILE Structure
METHYLSULFONYLACETONITRILE Chemical Properties
Melting point 81-84 °C(lit.)
Boiling point 360.6±25.0 °C(Predicted)
density 1.288±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Powder or Crystalline Powder
color White to off-white
Water Solubility Slightly soluble in water.
BRN 969929
CAS DataBase Reference2274-42-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,T
Risk Statements 20/21/22
Safety Statements 22-26-36
RIDADR UN 3439 6.1/PG 3
WGK Germany 3
HazardClass 6.1
PackingGroup III
HS Code 2926907090
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
METHYLSULFONYLACETONITRILE Usage And Synthesis
UsesMethylsulfonylacetonitrile is used in preparation of substituted pyrimidinylamino isoquinoline and naphthyridine compounds as inhibitors of mutant forms of EGFR.
Uses(Methylsulfonyl)acetonitrile was used in the synthesis of:
  • substituted δ-pyrone ring analogues
  • 4,9-dihydropyrrolo[2,1-b]quinazolines containing electron withdrawing groups at the 3-position
DefinitionChEBI: (methylsulfonyl)acetonitrile is an aliphatic nitrile.
METHYLSULFONYLACETONITRILE Preparation Products And Raw materials
Preparation Products3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine-->2-methyl-2-(methylsulfonyl)propanenitrile
AKOS BBS-00002840 2-PYRIDINESULFONYLACETONITRILE 2-PROPANESULPHONYLACETONITRILE 3-ETHOXY-2-(ISOPROPYLSULFONYL)ACRYLONITRILE 3-ETHOXY-2-(PROPYLSULFONYL)ACRYLONITRILE SODIUM (4-CHLOROPHENYL)[2-NITRILO(OXIDO)ETHANIMIDOYL]DIOXO-LAMBDA6-SULFANE (PHENYLSULFONYL)ACETONITRILE 2-(2-NAPHTHYLSULFONYL)ACETONITRILE N-HEXANESULFONYLACETONITRILE 3-ETHOXY-2-(2-NAPHTHYLSULFONYL)ACRYLONITRILE 2-[(4-CHLOROBENZYL)SULFONYL]ACETONITRILE 2-(TERT-BUTYLSULFONYL)-3-ETHOXYACRYLONITRILE 4-(Methylphenyl)sulfonylacetonitrile SULPHONYLDIACETONITRILE 2-(TERT-BUTYLSULFONYL)ACETONITRILE THIOPHENE-2-SULFONYLACETONITRILE METHYLSULFONYLACETONITRILE 1-PROPANESULPHONYLACETONITRILE
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