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| | BERGAPTOL Basic information |
| | BERGAPTOL Chemical Properties |
| Melting point | 287-290°C | | Boiling point | 311.9±11.0 °C(Predicted) | | density | 1.526±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 6.80±0.20(Predicted) | | form | neat | | color | Pale Beige to Pale Brown | | BRN | 190104 | | LogP | 1.405 (est) |
| | BERGAPTOL Usage And Synthesis |
| Uses | A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 and 42.93 μM, respectively. Recent studies suggest that it may have antiproliferative and anticancer properties. | | Definition | ChEBI: Bergaptol is a member of psoralens and a 5-hydroxyfurocoumarin. It is a conjugate acid of a bergaptol(1-). | | target | CYP3A4 |
| | BERGAPTOL Preparation Products And Raw materials |
| Raw materials | 7H-Furo(3,2-g)benzopyran-7-one, 5-((3,7-dimethyl-2,6-octadienyl)oxy)-, (E)--->Isoimperatorin-->4-[[(2E,5E)-7-Hydroxy-3,7-dimethyl-2,5-octadien-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one-->6',7'-DihydroxybergaMottin-->Bergamotine-->Notopterol-->Bergapten | | Preparation Products | ISOBERGAPTEN-->D-glucose |
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