ChemicalBook Product Catalog Organic Chemistry Carboxylic acids and derivatives Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-

Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Basic information
Product Name:Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
Synonyms:PUN 90488;Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-;Thalidomide 4'-ether-alkylC5-acid;Thalidomide-O-C5-acid;6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexanoic acid
CAS:2087490-48-8
MF:C19H20N2O7
MW:388.37
EINECS:
Product Categories:
Mol File:2087490-48-8.mol
Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Structure
Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Chemical Properties
Boiling point 694.4±55.0 °C(Predicted)
density 1.423±0.06 g/cm3(Predicted)
pka4.73±0.10(Predicted)
Safety Information
MSDS Information
Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Usage And Synthesis
DescriptionPUN 90488, also known as Thalidomide 4'-ether-alkylC5-acid is a cereblon ligand with alkyl linker and terminal acid for onward chemistry. This product has no formal name at the moment.
storageStore at -20°C
Hexanoic acid, 6-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Preparation Products And Raw materials
1H-Isoindole-1,3(2H)-dione, 4-[(7-aminoheptyl)oxy]-2-(2,6-dioxo-3-piperidinyl)- Propanoic acid, 3-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- 1H-Isoindole-1,3(2H)-dione, 4-[(10-aminodecyl)oxy]-2-(2,6-dioxo-3-piperidinyl)- Thalidomide-O-C5-NH2 Pentanoic acid, 5-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- 4-((8-Aminooctyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Thalidomide-O-C6-NH2 TFA Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]- 4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride Thalidomide-linker 6 Thalidomide-linker 9 Thalidomide-O-C6-NH2
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