ChemicalBook Product Catalog Chemical Reagents Organic reagents Aromatics N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide

N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide

N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide Basic information
Product Name:N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide
Synonyms:(R,S)-N-[4-Cyano-3-(trifluoroMethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-MethylpropionaMide;N-[4-Cyano-3-(TrifluoroMethyl)Phenyl]-3-[(4-Fluorophenyl)thio]-2-Hydroxy-2-Methy-PropanaMide;N-[4-Cyano-3-trifluoroMethy phenyl]-S-(4-fluorophenylthio)-2-hydrdoxy-2-Methyl-propionaMide(ASH BicalutaMide);N-[4-cyano-3-(rifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2- hydroxy-2-methyl propan Amide;Bicalutamide EP Impurity J;N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropiomide;4-CYANO-3-TRIFLUOROMETHYL-N-[3-(4-FLUOROPHENYLTHIO)-2-HYDROXYL-2-METHYLPROPIONYL]ANILINE;(S)-N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-3-(4-FLUOROPHENYLTHIO)-2-HYDROXY-2-METHYLPROPANAMIDE
CAS:90356-78-8
MF:C18H14F4N2O2S
MW:398.37
EINECS:618-533-8
Product Categories:Aromatics;Intermediates & Fine Chemicals;(intermediate of bicalutamide);Bicalutamide;Pharmaceuticals
Mol File:90356-78-8.mol
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide Structure
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide Chemical Properties
Melting point 109-111°C
Boiling point 565.6±50.0 °C(Predicted)
density 1.43±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka12.31±0.29(Predicted)
color White
PH6.45 at 24℃ and 10g/L
LogP3.8 at 30℃
CAS DataBase Reference90356-78-8(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
HS Code 29242990
MSDS Information
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide Usage And Synthesis
Chemical PropertiesWhite Solid
UsesBicalutamide intermediate.
N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide Preparation Products And Raw materials
Raw materialsN-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide-->N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide
Bicalutamide Calcium thioglycolate 6-Mercaptopurine 3-Mercaptopropionic acid Sodium thioglycolate 2-Mercaptobenzothiazole 2-Ethylhexyl mercaptoacetate Thiosalicylic acid Trifluoromethyl (R)-Bicalutamide PHENYL VALERATE Mercaptoacetic acid Propionamide 2-Mercaptoethanol N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide Cyano CHLOROPHOSPHONAZO III Phenylhydrazine
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