2,2-Difluoroethanol

2,2-Difluoroethanol Basic information

Product Name:	2,2-Difluoroethanol
Synonyms:	2,2-Difluoroethanol,95%;2,2-Difluoroethanol 97%;2,2-Difluoroethanol97%;2,3-Difluoroethanol;1,1-Difluoro-2-hydroxyethane;2,2-Difluoroethan-1-ol 97%;ART-CHEM-BB B019710;AKOS B019710
CAS:	359-13-7
MF:	C2H4F2O
MW:	82.05
EINECS:	670-547-3
Product Categories:	Four-membered heterocyclic compound;bc0001
Mol File:	359-13-7.mol

2,2-Difluoroethanol Chemical Properties

Melting point	-28°C
Boiling point	95 °C
density	1.296
refractive index	1.338
Fp	3°C
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	soluble in chloroform, ethanol.
pka	13.00±0.10(Predicted)
form	clear liquid
color	Colorless to Almost colorless
Specific Gravity	1.296
BRN	1731617
CAS DataBase Reference	359-13-7(CAS DataBase Reference)
NIST Chemistry Reference	Difluoroethanol(359-13-7)
EPA Substance Registry System	2,2-Difluoroethanol (359-13-7)

Safety Information

Hazard Codes	F,T
Risk Statements	11-20/21/22-36/37/38
Safety Statements	16-36/37/39-45-60-37-33-26-7
RIDADR	1987
Hazard Note	Flammable
HazardClass	3
PackingGroup	II
HS Code	29055900

MSDS Information

Provider	Language
2,2-Difluoroethanol	English
ALFA	English

2,2-Difluoroethanol Usage And Synthesis

Chemical Properties	Colorless Liquid
Uses	2,2-Difluoroethanol is used as a chemical intermediates. It has wide applications in medicine and fluoropolymers.
Synthesis Reference(s)	Journal of Medicinal Chemistry, 23, p. 985, 1980 DOI: 10.1021/jm00183a005

2,2-Difluoroethanol Preparation Products And Raw materials

Raw materials	Difluoroacetaldehyde-->2,2-Difluoroethanol 1-formate-->Ethanol, 2,2-difluoro-1-methoxy--->2,2-Difluoroethyldifluoroacetate-->Difluoroacetic acid-->2-CHLORO-1,1-DIFLUOROETHANE-->2,2-DIFLUOROETHYL ACETATE-->Ethyl difluoroacetate-->DIFLUOROACETALDEHYDE ETHYL HEMIACETAL-->2-BROMO-1,1-DIFLUOROETHANE-->DIFLUOROACETYL FLUORIDE-->METHYL DIFLUOROACETATE-->Chlorodifluoroacetic acid ethyl ester
Preparation Products	2,2-DIFLUOROETHYL P-TOLUENESULFONATE

1-ETHOXY-2,2-DIFLUOROETHANOL Methyl trifluoroacetate THALLIUM(III) TRIFLUOROACETATE METHYL HEPTAFLUOROBUTYRATE 2,2,2-TRIFLUOROETHYL P-TOLUENESULFONATE 2-METHOXY-2-PHENYL-3,3,3-TRIFLUOROPROPIONITRILE Methyl pentafluoropropionate METHYL CHLORODIFLUOROACETATE ETHYL HEPTAFLUOROBUTYRATE (R)-(-)-2,2,2-TRIFLUORO-1-(9-ANTHRYL)ETHANOL 2,2,2-Trifluoroethyl acrylate Ethyl trifluoroacetate TRIMETHYLSILYL TRIFLUOROACETATE CHLORODIFLUOROACETIC ANHYDRIDE TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL 2-CHLORO-2,2-DIFLUOROETHANOL ETHYL PENTAFLUOROPROPIONATE BORON TRIS(TRIFLUOROACETATE)

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