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| | Dizocilpine Basic information |
| Product Name: | Dizocilpine | | Synonyms: | (5S)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5α,10α-imine;[5S,10R,(+)]-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine;[5S,10R,(+)]-10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5α,10α-imine;C13737;MK-801 (Dizocilpine);5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S,10R)-;Dizocilpine;Dizocilpine free base(MK801) | | CAS: | 77086-21-6 | | MF: | C16H15N | | MW: | 221.3 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 77086-21-6.mol |  |
| | Dizocilpine Chemical Properties |
| | Dizocilpine Usage And Synthesis |
| Uses | Neuroprotective. | | Definition | ChEBI: Dizocilpine is an organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory. It has a role as a NMDA receptor antagonist, an anaesthetic, an anticonvulsant, a nicotinic antagonist and a neuroprotective agent. It is a secondary amino compound and a tetracyclic antidepressant. It is a conjugate base of a dizocilpine(1+). |
| | Dizocilpine Preparation Products And Raw materials |
| Raw materials | 5H-Dibenzo[a,d]cyclohepten-5,10-imine, 5-(bromomethyl)-10,11-dihydro-, (5S,10R)--->5H-Dibenzo[a,d]cyclohepten-5,10-imine-12-carboxylic acid, 5-cyano-10,11-dihydro-, ethenyl ester, (5S,10R)--->5H-Dibenzo[a,d]cyclohepten-5,10-imine-5-methanol, 10,11-dihydro-, (5S,10R)- |
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