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| | 3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE Basic information |
| | 3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE Chemical Properties |
| Melting point | 136-137° | | Boiling point | 343.23°C (rough estimate) | | density | 1.2597 (rough estimate) | | refractive index | 1.6880 (estimate) | | storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | pKa 5.15(H2O,t =25) (Uncertain) | | form | Solid | | color | Red crystals | | Water Solubility | 904.20g/L(25 ºC) | | BCS Class | 2 | | Stability: | Light Sensitive | | InChIKey | QPFYXYFORQJZEC-FOCLMDBBSA-N | | EPA Substance Registry System | Phenazopyridine (94-78-0) |
| | 3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE Usage And Synthesis |
| Chemical Properties | Phenazopyridine is a red crystalline compound. Slightly soluble in water. | | Originator | Phenazopyridine
,AroKor Holdings Inc. | | Uses | An azo dye used in treatment of urinary tract infections. 3-(Phenylazo)-2,6-pyridinediamine is used as an analgesic (urinary tract).
| | Uses | An azo dye used in treatment of urinary tract infections. Used as an analgesic (urinary tract). | | Definition | ChEBI: A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorder
) and potential carcinogenicity. | | Manufacturing Process | Phenyldiazene chloride reacted with 2,6-diaminopyridine and in the result 2,6diamino-3-(phenylazo)pyridine was obtained.
In practice it is usually used as monohydrochloride. | | Brand name | Pyridium (Parke-Davis);Azo gantrisin;Azodine;Phenazo;Pyridiate;Pyronium;Sedural. | | Therapeutic Function | Urinary analgesic, Antiseptic, Diagnostic aid | | World Health Organization (WHO) | Phenazopyridine, an azo dye, was introduced in the 1950s as a
urinary antiseptic. It was withdrawn in Greece in 1984 on grounds that it has a
carcinogenic potential but it remains available in other countries, most frequently
as a constituent of combination products. | | Safety Profile | Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. Used as a local anesthetic. When heated to decomposition it emits toxic fumes of NOx. | | Shipping | UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3249 Medicine, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials. | | Incompatibilities | Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. |
| | 3-(PHENYLAZO)-2,6-PYRIDINEDIAMINE Preparation Products And Raw materials |
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