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| | CIS-ACONITIC ANHYDRIDE Basic information |
| Product Name: | CIS-ACONITIC ANHYDRIDE | | Synonyms: | 2-(2,5-diketo-3-furyl)acetic acid;2-(2,5-dioxofuran-3-yl)acetic acid;2-(2,5-dioxofuran-3-yl)ethanoic acid;cis-Aconitic anhydride,cis-Propene-1,2,3-tricarboxylic anhydride;cis-Prop-1-ene-1,2,3-tricarboxylic acid anhydride, (2,5-Dihydro-2,5-dioxofur-3-yl)acetic acid;2-(2,5-dioxo-2,5-dihydrofuran-3-yl)acetic acid;(2,5-Dihydro-2,5-dioxofur-3-yl)acetic acid;3-(Carboxymethyl)-2,5-dihydro-2,5-dioxofuran, cis-Aconitic anhydride , cis-Prop-1-ene-1,2,3-tricarboxylic anhydride | | CAS: | 6318-55-4 | | MF: | C6H4O5 | | MW: | 156.09 | | EINECS: | 228-663-3 | | Product Categories: | | | Mol File: | 6318-55-4.mol |  |
| | CIS-ACONITIC ANHYDRIDE Chemical Properties |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 3261 8/PG 2 | | WGK Germany | 3 | | F | 10-21 | | TSCA | Yes | | HazardClass | 8 | | PackingGroup | III | | HS Code | 2917198090 |
| | CIS-ACONITIC ANHYDRIDE Usage And Synthesis |
| Uses | cis-Aconitic anhydride is used in the preparation of poly(amino acid)-containing copolymers with gradient pH-sensitive side groups initiated by the amino groups in methoxy poly(ethylene glycol)-block-poly(L-lysine). It is also involved in the preparation of pH-sensitive anti-tumor prodrug nanoparticles by conjugation with D-alfa-tocopheryl polyethylene glycol 1000 succinate (TPGS). | | Purification Methods | Reflux it in xylene (7.5 parts) for 1hour, then evaporate and recrystallise the residue from *C6H6. Alternatively, reflux it in Ac2O, evaporate and recrystallise from *C6H6. It is sensitive to moisture. [IR: Groth & Dahlén Acta Chem Scand 21 291 1967, Malachowski & Maslowski Chem Ber 61 2523 1928, NMR: Gawron & Mahajan Biochemistry 5 2335 1966.] [Beilstein 18/8 V 530.] |
| | CIS-ACONITIC ANHYDRIDE Preparation Products And Raw materials |
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