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N-Acetyl carnosine

N-Acetyl carnosine Basic information
Product Name:N-Acetyl carnosine
Synonyms:(S)-2-(3-ACETYLAMINO-PROPIONYLAMINO)-3-(3H-IMIDAZOL-4-YL)-PROPIONIC ACID;n-acetyl carnosine;N-ACETYL-L-CARNOSINE;N-A-ACETYL-N-B-ALANYL-L-HISTIDINE;N-Aceyl-L-Carnosine;N-Acetyl camosine;NAC, N-a-Acetyl-N-b-alanyl-L-histidine;N-(N-acetyl-beta-alanyl)-L-histidine
CAS:56353-15-2
MF:C11H16N4O4
MW:268.27
EINECS:260-123-2
Product Categories:Amino Acids & Derivatives;Heterocycles;PROTECTED AMINO ACID & PEPTIDES;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:56353-15-2.mol
N-Acetyl carnosine Structure
N-Acetyl carnosine Chemical Properties
Melting point 209-210°C
Boiling point 775.9±60.0 °C(Predicted)
density 1.343±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Methanol (Slightly), Water (Slightly)
form Solid
pka3.08±0.10(Predicted)
color White to Off-White
InChIInChI=1/C11H16N4O4/c1-7(16)13-3-2-10(17)15-9(11(18)19)4-8-5-12-6-14-8/h5-6,9H,2-4H2,1H3,(H,12,14)(H,13,16)(H,15,17)(H,18,19)/t9-/s3
InChIKeyBKAYIFDRRZZKNF-DJEYLCQNNA-N
SMILES[C@H](C(=O)O)(NC(=O)CCNC(=O)C)CC1N=CNC=1 |&1:0,r|
Safety Information
MSDS Information
N-Acetyl carnosine Usage And Synthesis
DescriptionN-acetyl-L-Carnosine is a dipeptide and acetylated form of L-carnosine that has been found in heart and skeletal muscle and has antioxidant and anticataract activities. It reduces iron- and ascorbate-induced malondialdehyde (MDA) accumulation in liposomes when used at concentrations of 10 and 20 mM. Topical administration of N-acetyl-L-carnosine (1% v/v) reduces cortical opacities in a canine model of age-related cataracts.
Chemical PropertiesWhite Crystalline Solid
UsesN-acetyl-L-Carnosine is used in the treatment of cataracts and in the treatment of UV-induced immunosuppression
DefinitionChEBI: A dipeptide that is the N-acetyl derivative of carnosine.
N-Acetyl carnosine Preparation Products And Raw materials
Raw materialsAC-BETA-ALA-OH-->L-Histidine
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride N-Acetylglycine N-Acetyl-L-glutamic acid N-Acetyl-D-galactosamine Acetyl-resveratrol Acetylspiramycin L-Carnosine Acetylcholine Acetaminophen ACETAMINOPHENOL BP/USP Acetylacetone Acetyl chloride Acetylsalicylic acid Acetyl coenzyme A sodium salt N-Acetyl carnosine
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