(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID

(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID Basic information

Product Name:	(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
Synonyms:	(2R,4S)-N-Boc-trans-4-hydroxy-D-proline;(2R,4S)-N-Boc-cis-4-hydroxy-D-proline;Boc-D-trans-Hyp-OH;N-Boc-trans-4-hydroxy-D-proline 95+%;(2R,4S)-N-Boc-4-hydroxy-D-proline;(2R,4S)-4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester;N-Boc-trans-D-Hyp-OH;1-tert-Butoxycarbonyl-(2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid
CAS:	147266-92-0
MF:	C10H17NO5
MW:	231.25
EINECS:	803-000-6
Product Categories:
Mol File:	147266-92-0.mol

(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID Chemical Properties

Melting point	123°C
Boiling point	390.9±42.0 °C(Predicted)
density	1.312±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	3.80±0.40(Predicted)
form	solid
color	White
optical activity	[α]/D +70°, c = 0.617 g/mL in methanol

Safety Information

MSDS Information

(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID Usage And Synthesis

Chemical Properties	White powder
Uses	Boc protected Proline derivative.

(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials	(4R)-4-Hydroxy-1-Boc-D-proline ethyl ester-->trans-4-Hydroxy-D-proline-->Di-tert-butyl dicarbonate-->L-Hydroxyproline
Preparation Products	(1R,4R)-tert-Butyl 3-oxo-2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate-->N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER

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