DL-Aspartic acid

DL-Aspartic acid Basic information

Product Name:	DL-Aspartic acid
Synonyms:	H-D-ASP-OH;H-DL-ASP-OH;DL-ASPARTIC ACID;DL-ASPARAGINIC ACID;D,L-ASP;DL-AMINOSUCCINIC ACID;DL-2-AMINOBUTANEDIOIC ACID;D-ASPARAGINIC ACID
CAS:	617-45-8
MF:	C4H7NO4
MW:	133.1
EINECS:	210-513-3
Product Categories:	nutritional supplement;amino acid;Amino Acids Derivatives;aspartic acid;organic acids;pharmaceutical intermediate;Aspartic acid [Asp, D];alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids;API
Mol File:	617-45-8.mol

DL-Aspartic acid Chemical Properties

Melting point	300 °C
alpha	[α]D20 0±0.3° (c=5, dil. HCl)
Boiling point	245.59°C (rough estimate)
density	1.6622
refractive index	1.4540 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	SOLUBLE
form	Crystalline Low Melting Mass
pka	2.28±0.23(Predicted)
color	Yellow
Odor	acid taste
Water Solubility	SOLUBLE
BRN	774618
LogP	-1.075 (est)
CAS DataBase Reference	617-45-8(CAS DataBase Reference)
NIST Chemistry Reference	Dl-aspartic acid(617-45-8)
EPA Substance Registry System	Aspartic acid (617-45-8)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	22-24/25-36-26
WGK Germany	3
RTECS	CI9097800
TSCA	Yes
HS Code	29224995
Toxicity	LD50 ipr-mus: >6 g/kg KHFZAN 24(5),17,90

MSDS Information

Provider	Language
DL-Aspartic acid	English
SigmaAldrich	English
ACROS	English
ALFA	English

DL-Aspartic acid Usage And Synthesis

Chemical Properties	White crystalline powder
Uses	Food additive.
Definition	ChEBI: An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent
Biological Functions	DL-Aspartic acid (DL-Asp) is a racemic mixture of the proteinogenic amino acid L-aspartate and the non-proteinogenic amino acid D-aspartate. DL-Aspartic acid is used in studies on factors and conditions that enhance semen and sperm quality.
Hazard	Very low toxicity.
Biochem/physiol Actions	DL-Aspartic acid (DL-Asp) is a racemic mixture of the proteinogenic amino acid L-aspartate and the non-proteinogenic amino acid D-aspartate. DL-Aspartic acid is used in studies on factors and conditions that enhance semen and sperm quality.
Safety Profile	Very low toxicity byintraperitoneal route. When heated to decompositionemits toxic fumes of NOx.
Purification Methods	Likely impurities are glutamic acid, cystine and asparagine. Crystallise the acid from water by adding 4 volumes of EtOH and dry it at 110o. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1856 1961, Beilstein 4 IV 2998, 3000.]

DL-Aspartic acid Preparation Products And Raw materials

Raw materials	Sulfuric acid-->Maleic anhydride-->Activated carbon-->Benzylamine-->2,3-DICHLORO-5,8-DIHYDROXY-1,4-NAPHTHOQUINONE-->Maleic acid-->L-Aspartic acid
Preparation Products	L-Aspartic acid-->3-N-Boc-aminopyrrolidine-->Magnesium D,L-Hydrogenaspartate Tetrahydrate-->3-oxopropanoic acid-->H-DL-ASP(OME)-OH HCL-->HYDANTOIN-5-ACETIC ACID-->CHLOROSUCCINIC ACID-->2-(4-OXO-2-THIOXO-THIAZOLIDIN-3-YL)-SUCCINIC ACID-->D,L-ASPARTIC ACID DIBENZYL ESTER-P-TOLUENESULFONATE

Hyaluronic acid Ethyl 2-(Chlorosulfonyl)acetate DL-Aspartic acid magnesium salt tetrahydrate L-Aspartic acid Ascoric Acid DL-Malic acid Poly-L-aspartic acid Folic acid DL-Tryptophan Diethyl succinosuccinate D-Aspartic acid Disodium succinate Calcium L-aspartate L-ASPARTIC ACID Potassium hydrogen DL-aspartate Succimer meso-2,3-Dibromosuccinic acid Citric acid

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