5-Methyl-2-pyrazinecarboxylic acid

5-Methyl-2-pyrazinecarboxylic acid Basic information

Product Name:	5-Methyl-2-pyrazinecarboxylic acid
Synonyms:	5-Methylpyrazine-2-carboxylicacid(Acipimoxintermediate);5-Methyl-2-pyrazinecarboxylic acid,99%;5--2- Methylpyrazine carboxylic acid;5-Methyl-2-pyrazinecarboxylic acid 98%;Methyl-2-pyrazinecarboxylic;2-Methyl-5-Pyrazine-Carboxylic Acid (5MPC);5-Methylparazine-2-carboxylic acid;5-Methyl-2-pyrazinecarboxylic acid, 99% 5GR
CAS:	5521-55-1
MF:	C6H6N2O2
MW:	138.12
EINECS:	413-260-9
Product Categories:	Mono- & Polyalkylpyrazines;Pyrazinecarboxylic Acid & Derivatives;Building Blocks;Heterocyclic Building Blocks;Aromatics;Bases & Related Reagents;Nucleotides;Carboxylic Acids;Pyrazines, Pyrimidines & Pyridazines;Aromatics Compounds;Pyrazines;Organic acids;Carboxylic Acids;Pyrazines, Pyrimidines & Pyridazines;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Acids and Derivatives;Heterocycles;5521-55-1
Mol File:	5521-55-1.mol

5-Methyl-2-pyrazinecarboxylic acid Chemical Properties

Melting point	167-171 °C(lit.)
Boiling point	253.51°C (rough estimate)
density	1.3471 (rough estimate)
refractive index	1.5100 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	3.53±0.10(Predicted)
form	Amorphous Powder
color	Orange
BRN	116005
LogP	-0.254 (est)
CAS DataBase Reference	5521-55-1(CAS DataBase Reference)
NIST Chemistry Reference	2-Methylpyrazine-5-carboxylic acid(5521-55-1)

Safety Information

MSDS Information

5-Methyl-2-pyrazinecarboxylic acid Usage And Synthesis

Chemical Properties	Pale Brown Powder
Uses	5-Methyl-2-pyrazinecarboxylic acid may be used in the preparation of novel europium(III) complexes, (5-methyl-2-pyrazinecarboxylato) (phenanthroline)europium(III). It may be used in the synthesis of Ln-metal organic frameworks (MOFs).
General Description	5-Methyl-2-pyrazinecarboxylic acid is a pyrazine derivative. Simultaneous membrane based solvent extraction (MBSE) and membrane based solvent stripping (MBSS) of 5-methyl-2-pyrazine carboxylic acid (MPCA) has been studied. Mechanism of pertraction of MPCA through layered bulk liquid membranes has been studied. MPCA reacts with Ln(NO₃)₃·6H₂O and K₄[W(CN)₈]·2H₂O to form unique three-dimensional network structure which contains open channels.
Synthesis	5-Methylpyrazine-2-carboxylic acid is an intermediate of the lipid-lowering drug amoximus. It can be prepared by electrolytic oxidation of 2,5-dimethyl or 2-methyl-5-(substituted) methylpyrazine.

5-Methyl-2-pyrazinecarboxylic acid Preparation Products And Raw materials

Raw materials	2-Methylpyrazine-->Pyrazinemethanol, 5-methyl-, acetate (ester)-->3-HYDROXY-5-METHYLPYRAZINE-2-CARBOXYLIC ACID-->diethyl pyrazine-2,5-dicarboxylate-->Pyrazine-2,5-dicarboxylic acid-->2-(chloromethyl)-5-methylpyrazine hydrochloride-->5-Methyl-2,3-pyrazinedicarboxylic acid-->2-(CHLOROMETHYL)-5-METHYLPYRAZINE-->5-Methyl-2-pyrazinemethanol-->Pyrazinecarboxamide, 3,4-dihydro-5-methyl-3-oxo- (9CI)
Preparation Products	Acipimox-->2-Pyrazinecarboxylic acid-->2-Bromo-5-methylpyrazine-->METHYL 5-METHYLPYRAZINE-2-CARBOXYLATE-->tert-Butyl [5-(hydroxymethyl)pyrazin-2-yl]carbamate

Login