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| | 3-Hydroxypyridine Basic information |
| | 3-Hydroxypyridine Chemical Properties |
| Melting point | 125-128 °C (lit.) | | Boiling point | 280-281 °C(lit.) | | density | 1.1418 (rough estimate) | | refractive index | 1.5939 (estimate) | | Fp | 173°C | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | 33g/l | | pka | 4.79, 8.75(at 20℃) | | form | Crystalline Powder | | color | Beige to brown | | PH | 6.0-6.5 (33g/l, H2O, 20℃) | | Water Solubility | 32.26g/L(20 ºC) | | BRN | 105699 | | LogP | 0.480 | | CAS DataBase Reference | 109-00-2(CAS DataBase Reference) | | NIST Chemistry Reference | 3-Pyridinol(109-00-2) | | EPA Substance Registry System | 3-Pyridinol (109-00-2) |
| | 3-Hydroxypyridine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal. Soluble in alcohol and water, slightly soluble in ether and benzene. It becomes a red solution when it encounters ferric chloride, and it is easy to decompose in the air. | | Uses | 3-Hydroxypyridine (cas# 109-00-2) is a compound useful in organic synthesis. | | Preparation | 3-hydroxypyridine was prepared by reacting furfurylamine with H2O2 in the presence of HCl, followed by hydrolysis. The optimal conditions were found as fellows: molar ratio of furfurylamine: HCl : H2O2 = 1 : 5 : 1.1, and H2O2 added dropwisely at 0-5 °C, and then refluxed at 100-105 °C for 0.5 h. | | Definition | ChEBI: 3-Hydroxypyridine is a monohydroxypyridine that is pyridine in which the hydrogen at position 3 has been replaced by a hydroxy group. It has been detected as a thermal degradation product from the smoke of the burning leaves of Salvia divinorum, a Mexican psychoactive plant. | | Brand name | Ventavis (Schering). | | Purification Methods | Crystallise 3-hydroxypyridine from *C6H6, water or EtOH. [Beilstein 21 III/IV 402, 21/2 V 68.] |
| | 3-Hydroxypyridine Preparation Products And Raw materials |
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