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| | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Basic information |
| | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Chemical Properties |
| Melting point | >242°C (dec.) | | density | 2?+-.0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | 1% sodium bicarbonate: 50 mg/mL | | form | powder | | pka | 1.03±0.60(Predicted) | | color | white | | Stability: | Hygroscopic |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-26-36 | | WGK Germany | 3 | | HS Code | 29349990 | | Toxicity | The product
formed by the guanylate cyclase enzymes from GTP. It is
a cellular “second messenger,” participating in the regulation
of many intracellular events. Toxicants (e.g., nitroprusside)
may cause physiological changes by interfering with aspects of cyclic GMP metabolism. |
| | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Usage And Synthesis |
| Chemical Properties | White powder | | Uses | Guanosine 3'',5''-Cyclic Monophosphate is an intracellular second messenger which are involved in the transduction of a diverse array of stimuli, mediating metabolic and growth regulation. | | Definition | ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP. | | Biochem/physiol Actions | An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG). |
| | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Preparation Products And Raw materials |
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